Darian-Smith, E and Howie, A and Abell, RG and Kerr, N and Allen, PL and Vote, BJ and Toh, T, Intraocular pressure during femtosecond laser pretreatment: Comparison of glaucomatous eyes and nonglaucomatous eyes, Journal of Cataract and Refractive Surgery, 41, (2) pp. 272-277. ISSN 0886-3350 (2015) [Refereed Article]
Copyright 2015 ASCRS and ESCRS
Purpose: To compare changes in intraocular pressure (lOP) during femtosecond laser pretreatment of cataract between glaucomatous eyes and nonglaucomatous eyes.
Setting: Launceston Eye Institute and Launceston Eye Hospital, Launceston, Australia.
Design: Nonrandomized interventional prospective case series.
Methods: Patients with clinically stable primary open-angle glaucoma (POAG) having femtosecond laser pretreatment were compared with a concurrent cohort of patients with healthy eyes having the same procedure. Pretreatment was performed using a fluid-filled optical docking system (Liquid Optics Interface). With the patient supine, the lOP was measured at 4 time points using a rebound tonometer (lcare Pro).
Results: The study comprised 143 eyes of 97 patients. Forty-three eyes (30.1%) had documented glaucoma. The mean baseline lOP was 20.2 mm Hg ± 4.2 (SO) in glaucomatous eyes and 18.9 ± 4.0 mm Hg in nonglaucomatous eyes (P = .06). The mean change in lOP values between each time frame and baseline was as follows: vacuum-on, 13.8 ± 9.9 mm Hg and 11.1 ± 6.9 mm Hg, respectively (P = .06); after treatment, 17.4 ± 7.4 mm Hg and 14.1 ± 7.2 mm Hg, respectively (P = .014); after undocking of vacuum, 9.9 ± 5.4 mm Hg and 8.7 ± 5.7 mm Hg, respectively (P = .24).
Conclusions: Femtosecond pretreatment caused a greater transient rise in lOP after treatment and a higher residual lOP after vacuum undocking in glaucomatous eyes than in nonglaucomatous eyes. This is well tolerated short term; however, long-term implications for eyes with glaucoma are unknown at present.
|Item Type:||Refereed Article|
|Keywords:||intraocular pressure, femtosecond laser, glaucomatous eyes|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Ophthalmology and optometry|
|Objective Group:||Clinical health|
|Objective Field:||Treatment of human diseases and conditions|
|UTAS Author:||Darian-Smith, E (Dr Erica Darian-Smith)|
|UTAS Author:||Howie, A (Mr Allister Howie)|
|UTAS Author:||Allen, PL (Dr Penny Allen)|
|UTAS Author:||Vote, BJ (Dr Brendan Vote)|
|Web of Science® Times Cited:||13|
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