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Characterization of polymer monoliths containing embedded nanoparticles by scanning transmission X-ray microscopy (STXM)
journal contribution
posted on 2023-05-18, 03:31 authored by Arrua, RD, Hitchcock, AP, Hon, WB, West, M, Emily HilderEmily HilderThe structural and chemical homogeneity of monolithic columns is a key parameter for high efficiency stationary phases in liquid chromatography. Improved characterization techniques are needed to better understand the polymer morphology and its optimization. Here the analysis of polymer monoliths by scanning transmission X-ray microscopy (STXM) is presented for the first time. Poly(butyl methacrylate-co-ethyleneglycoldimethacrylate) [poly(BuMA-co-EDMA)] monoliths containing encapsulated divinylbenzene (DVB) nanoparticles were characterized by STXM, which gives a comprehensive, quantitative chemical analysis of the monolith at a spatial resolution of 30 nm. The results are compared with other methods commonly used for the characterization of polymer monoliths [scanning electron microscopy (SEM), transmission electron microscopy (TEM), mercury porosimetry, and nitrogen adsorption]. The technique permitted chemical identification and mapping of the nanoparticles within the polymeric scaffold. Residual surfactant, which was used during the manufacture of the nanoparticles, was also detected. We show that STXM can give more in-depth chemical information for these types of materials and therefore lead to a better understanding of the link between polymer morphology and chromatographic performance.
History
Publication title
Analytical ChemistryVolume
86Issue
6Pagination
2876-2881ISSN
0003-2700Department/School
School of Natural SciencesPublisher
Amer Chemical SocPlace of publication
1155 16th St, NW, Washington, USA, Dc, 20036Rights statement
Copyright 2014 American Chemical SocietyRepository Status
- Restricted