eCite Digital Repository

Chemoprevention Targeting Epigenetic Changes in Cancer


Poke, FS and Holloway, AF, Chemoprevention Targeting Epigenetic Changes in Cancer, Field Cancerization: Basic Science and Clinical Applications, Nova Science Publishers, Gabriel D. Dakubo (ed), New York, pp. 559-575. ISBN 978-1-61761-006-6 (2011) [Research Book Chapter]

Copyright Statement

Copyright 2010 Nova Science Publishers, Inc

Official URL:


The presence of multiple cancers in one patient has excited the interest of many investigators, and considerable literature has accumulated on this subject. The scientific concepts and clinical importance of field cancerization are the subject matter of this book. This book is a compendium of importance to oncologists and cancer researchers and caregivers. Existent knowledge on cancer biology and therapy has been vastly expanded by this concept of cancer evolution. Expanding "super-competitors", multistep carcinogenesis, and stem cell theories are some novel mechanistic models of carcinogenesis discussed in this book. Extensively covered in this book as well, are the cellular and molecular changes representative of field cancerization in several cancers, including hematologic and pediatric cancers.

Item Details

Item Type:Research Book Chapter
Research Division:Biological Sciences
Research Group:Genetics
Research Field:Epigenetics (incl. genome methylation and epigenomics)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Poke, FS (Dr Fiona Poke)
UTAS Author:Holloway, AF (Associate Professor Adele Holloway)
ID Code:76585
Year Published:2011
Deposited By:Menzies Institute for Medical Research
Deposited On:2012-03-08
Last Modified:2017-10-16

Repository Staff Only: item control page