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Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain
journal contribution
posted on 2023-05-17, 03:07 authored by Howells, C, Adrian WestAdrian West, Chung, RSNeuronal growth-inhibitory factor, later renamed metallothionein-3, is one of four members of the mammalian metallothionein family. Metallothioneins are a family of ubiquitous, low-molecular-weight, cysteine-rich proteins. Although neuronal growth-inhibitory factor shares metal-binding and reactive oxygen species scavenging properties with the other metallothioneins, it displays several distinct biological properties. In this review, we examine the recent developments regarding the function of neuronal growth-inhibitory factor within the brain, particularly in response to brain injury or during neurodegenerative disease progression.
History
Publication title
The F E B S JournalVolume
277Issue
14Pagination
2931-2939ISSN
1742-464XDepartment/School
Menzies Institute for Medical ResearchPublisher
Wiley-Blackwell Publishing Ltd.Place of publication
United KingdomRights statement
The definitive published version is available online at: http://interscience.wiley.comRepository Status
- Restricted