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Probing the kinetic performance limits for ion chromatography. I. Isocratic conditions for small ions


Causon, TJ and Hilder, EF and Shellie, RA and Haddad, PR, Probing the kinetic performance limits for ion chromatography. I. Isocratic conditions for small ions, The Journal of Chromatography A, 1217, (31) pp. 5057-5062. ISSN 0021-9673 (2010) [Refereed Article]

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DOI: doi:10.1016/j.chroma.2010.05.066


The first use of the kinetic plot method to characterise the performance of ion-exchange columns for separations of small inorganic anions is reported. The influence of analyte type (mono- and divalent), particle size (5 and 9 m), temperature (30 and 60 C) and maximum pressure drop upon theoretical extrapolations was investigated using data collected from anion-exchange polymeric particulate columns. The quality of extrapolations was found to depend upon the choice of analyte, but could be verified by coupling a series of columns to demonstrate some practical solutions for ion chromatography separations requiring relatively high efficiency. Separations of small anions yielding 2540,000 theoretical plates using five serially connected columns (9 m particles) were obtained and yielded deviations of <15% from the kinetic plot predictions. While this approach for achieving high efficiencies results in a very long analysis time (t0 = 21 min), separations yielding approximately 10,000 theoretical plates using two serially connected columns (t0 < 5 min) were shown to be more practically useful for isocratic separations when compared to use of a single column operated at optimum linear velocity (t0 > 10 min).

Item Details

Item Type:Refereed Article
Keywords:Ion-exchange; Ion chromatography; Kinetic performance; Isocratic
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Causon, TJ (Mr Timothy Causon)
UTAS Author:Hilder, EF (Professor Emily Hilder)
UTAS Author:Shellie, RA (Associate Professor Robert Shellie)
UTAS Author:Haddad, PR (Professor Paul Haddad)
ID Code:64328
Year Published:2010
Funding Support:Australian Research Council (DP0663781)
Web of Science® Times Cited:9
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2010-07-16
Last Modified:2014-11-21

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