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The 1984 Tasmanian Insulin-Treated Diabetes-Mellitus Prevalence Cohort - An 8 and a Half Year Mortality Follow-Up Investigation


Riley, MD and McCarty, DJ and Couper, DJ and Humphrey, ARG and Dwyer, T and Zimmet, P, The 1984 Tasmanian Insulin-Treated Diabetes-Mellitus Prevalence Cohort - An 8 and a Half Year Mortality Follow-Up Investigation, Diabetes Research and Clinical Practice, 29, (1) pp. 27-35. ISSN 0168-8227 (1995) [Refereed Article]

DOI: doi:10.1016/0168-8227(95)01106-N


Total mortality and underlying cause of death were examined in a population-based prevalence cohort (n = 1232) of Tasmanians with insulin-treated diabetes mellitus. Eight and a half years after the establishment of the registry, the cause of death based on death certificate information was determined for the overall cohort and for three classification groups of insulin-treated diabetes: Group A - childhood-onset IDDM cases; Group B - adult-onset IDDM cases; and Group C - adult-onset insulin-treated NIDDM cases. A total of 378 deaths occurred, providing an overall SMR of 2.2 (95% CI 2.0-2.4) compared to the Tasmanian population. Diabetic females experienced a higher SMR (2.6, 95% CI 2.3-3.0) than diabetic males (1.9, 95% Cl 1.6-2.2). The all-cause SMRs for the diabetic classification groups were 4.6 (95% CI 3.4-6.1) in Group A, 1.8 (95% CI 1.5-2.1) in Group B, and 2.2 (95% CI 1.9-2.6) in Group C. After adjusting for age, gender and duration of diabetes, the mortality in Group C was significantly higher compared to Group B (odds ratio 1.6, 95% CI 1.2-2.3). This study indicates that people with childhood-onset IDDM experience 4.6 times the death rate compared to the Tasmanian population and that the excess mortality is most pronounced in females.

Item Details

Item Type:Refereed Article
Research Division:Health Sciences
Research Group:Epidemiology
Research Field:Epidemiology not elsewhere classified
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Riley, MD (Mr Malcolm Riley)
UTAS Author:Couper, DJ (Dr David Couper)
UTAS Author:Dwyer, T (Professor Terry Dwyer)
ID Code:5784
Year Published:1995
Web of Science® Times Cited:12
Deposited By:Menzies Centre
Deposited On:1995-08-01
Last Modified:2011-08-25

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