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Recent advances in polymer monoliths for ion-exchange chromatography

journal contribution
posted on 2023-05-16, 23:50 authored by Nordborg, AMM, Emily HilderEmily Hilder
The use of polymeric materials in ion-exchange chromatography applications is advantageous because of their typically high mechanical stability and tolerance of a wide range of pH conditions. The possibility of using polymeric monoliths in ion-exchange chromatography is therefore obvious and many of the same strategies developed for polymeric particles have been adapted for use with polymeric monoliths. In this review different strategies for the synthesis of polymeric monoliths with ion-exchange functionality are discussed. The incorporation of ionexchange functionality by co-polymerization is included, as also are different post-polymerization alterations to the monolith surface such as grafting. The formulations and strategies presented include materials intended for use in analytical separations in ion-exchange chromatography, sample pre-treatment or enrichment applications, and materials for capillary electrochromatography. Finally, examples of the use of polymeric monoliths in ion-exchange chromatography applications are included with examples published in the years 2003 to 2008.

History

Publication title

Analytical and Bioanalytical Chemistry

Volume

394

Pagination

71-84

ISSN

1618-2642

Department/School

School of Natural Sciences

Publisher

Springer

Place of publication

Germany

Rights statement

The original publication is available at www.springerlink.com

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

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