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Health related quality of life of people receiving highly active antiretroviral therapy in Southwest Ethiopia

Citation

Desta, A and Biru, TT and Kefale, AT, Health related quality of life of people receiving highly active antiretroviral therapy in Southwest Ethiopia, PLoS ONE, 15, (8) Article e0237013. ISSN 1932-6203 (2020) [Refereed Article]


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Copyright Statement

Copyright 2020 Desta et al. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.1371/journal.pone.0237013

Abstract

Background

Highly Active Antiretroviral Therapy (HAART) is a standard of HIV management to suppress viral load and delay progression to AIDS. However, questions have been raised about the use of antiretroviral therapy and how it affects quality of life (QoL) of people living with HIV/AIDS (PLWHA). The study hence aimed to assess the QoL of PLWHA who were taking HAART at Mizan–Tepi University Teaching Hospital (MTUTH) and identify factors associated with QoL.

Methods

A cross sectional study was conducted among PLWHA receiving HAART at MTUTH from March 04-April 1, 2018. Patients were recruited consecutively and interviewed with structured questionnaire. A data abstraction tool was used to extract data from patient medical records. Quality of life was assessed using the World Health Organization Quality of Life HIV- BREF (WHOQOL-HIV-BREF) standard tool. Data was entered to Epi-Info version 3.5.3 and analyzed using SPSS version 22 for windows. A multivariable logistic regression analysis was fitted to identify factors associated with QoL. A statistical significance was established at a p value <0.05.

Results

A total of 240 participants with the mean age of 35.11 (SD = 9.08) years were included in the study. This study found that 57.1% of the patients had high global score of QoL. Patients with normal current health (AOR = 3.38, 95% CI = 1.56–7.31)) and having family support (AOR = 3.12, 95% CI = 1.51–6.46) were positively associated with high global score of QoL, while patients with low HAART adherence (AOR = 0.40, 95%, CI = 0.19–0.86) were negatively associated with high global score of QoL.

Conclusion

The study revealed that more than half of the participants had high global score of QoL. Normal current health and family support were associated with better global score of QoL, while low HAART adherence was found to be associated with the lower global score of QoL.

Item Details

Item Type:Refereed Article
Keywords:HIV, quality of life, Ethiopia
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Health services and systems not elsewhere classified
Objective Division:Health
Objective Group:Evaluation of health and support services
Objective Field:Evaluation of health outcomes
UTAS Author:Kefale, AT (Mr Adane Kefale)
ID Code:142699
Year Published:2020
Web of Science® Times Cited:1
Deposited By:Pharmacy
Deposited On:2021-02-05
Last Modified:2021-03-24
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