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Maternal exposure to ambient air pollution and pregnancy complications in Victoria, Australia

Citation

Melody, SM and Wills, K and Knibbs, LD and Ford, J and Venn, A and Johnston, F, Maternal exposure to ambient air pollution and pregnancy complications in Victoria, Australia, International Journal of Environmental Research and Public Health, 17, (7) Article 2572. ISSN 1661-7827 (2020) [Refereed Article]


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Copyright Statement

Copyright 2020 The Authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.3390/ijerph17072572

Abstract

The relationship between maternal exposure to ambient air pollution and pregnancy complications is not well characterized. We aimed to explore the relationship between maternal exposure to ambient nitrogen dioxide (NO2) and fine particulate matter (PM2.5) and hypertensive disorders of pregnancy, gestational diabetes mellitus (GDM) and placental abruption. Using administrative data, we defined a state-wide cohort of singleton pregnancies born between 1 March 2012 and 31 December 2015 in Victoria, Australia. Annual average NO2 and PM2.5 was assigned to maternal residence at the time of birth. 285,594 singleton pregnancies were included. An IQR increase in NO2 (3.9 ppb) was associated with reduced likelihood of hypertensive disorders of pregnancy (RR 0.89; 95%CI 0.86, 0.91), GDM (RR 0.92; 95%CI 0.90, 0.94) and placental abruption (RR 0.81; 95%CI 0.69, 0.95). Mixed observations and smaller effect sizes were observed for IQR increases in PM2.5 (1.3 g/m3) and pregnancy complications; reduced likelihood of hypertensive disorders of pregnancy (RR 0.95; 95%CI 0.93, 0.97), increased likelihood of GDM (RR 1.02; 95%CI 1.00, 1.03) and no relationship for placental abruption. In this exploratory study using an annual metric of exposure, findings were largely inconsistent with a priori expectations and further research involving temporally resolved exposure estimates are required.

Item Details

Item Type:Refereed Article
Keywords:air pollution, pregnancy, gestational diabetes mellitus, preeclampsia, placental abruption
Research Division:Environmental Sciences
Research Group:Pollution and contamination
Research Field:Pollution and contamination not elsewhere classified
Objective Division:Health
Objective Group:Specific population health (excl. Indigenous health)
Objective Field:Women's and maternal health
UTAS Author:Melody, SM (Dr Shannon Melody)
UTAS Author:Wills, K (Dr Karen Wills)
UTAS Author:Venn, A (Professor Alison Venn)
UTAS Author:Johnston, F (Associate Professor Fay Johnston)
ID Code:139154
Year Published:2020
Web of Science® Times Cited:3
Deposited By:Menzies Institute for Medical Research
Deposited On:2020-05-28
Last Modified:2021-03-16
Downloads:6 View Download Statistics

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