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Health state utilities for economic evaluation of bariatric surgery: a comprehensive systematic review and meta-analysis
journal contribution
posted on 2023-05-20, 12:01 authored by Qing Xia, Julie CampbellJulie Campbell, Hasnat AhmadHasnat Ahmad, Lei SiLei Si, Barbara de GraaffBarbara de Graaff, Petr OtahalPetr Otahal, Andrew PalmerAndrew PalmerHealth state utilities (HSUs) are health economic metrics that capture and assess health-related quality of life (HRQoL). They are essential in health-economic evaluations when calculating quality-adjusted life years. We investigated published studies reporting bariatric surgery-related HSUs elicited through direct or indirect (multiattribute utility instrument [MAUI]) patient-reported methods (PROSPERO registration number: CRD42019131725). Mean HSUs for different time points and HSU changes over time (where feasible) were meta-analysed using random-effects models. Of the 950 potentially relevant identified studies, n = 28 (2004-2018) qualified for data extraction, with n = 85 unique HSUs elicited mainly from the EQ-5D (88%). Most (75%) studies were published after 2013. The follow-up duration varied between studies and was often limited to 12 months. The pooled mean HSU was 0.72 (0.67-0.76) at baseline/presurgery (n = 18) and 0.84 (0.79-0.89) one-year postsurgery (n = 11), indicating a 0.11 (0.09-0.14) utility unit increment. EQ-5D showed the similar results. This positive difference can be partially explained by BMI and/or co-morbidities status improvement. This study provides a valuable summary of HSUs to future bariatric surgery-related cost-utility models. However, more well-designed higher-quality bariatric-related HSU studies are expected for future reviews to improve the available evidence. We suggest that researchers select an MAUI that is preferentially sensitive to the study population.
History
Publication title
Obesity ReviewsVolume
21Issue
8Article number
e13028Number
e13028Pagination
1-14ISSN
1467-7881Department/School
Menzies Institute for Medical ResearchPublisher
Wiley-Blackwell Publishing Ltd.Place of publication
United KingdomRights statement
Copyright 2020 World Obesity Federation. This is the peer reviewed version of the following article, which has been published in final form at http://doi.org/10.1111/obr.13028. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.Repository Status
- Restricted