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Microarrays and stage conversion in Toxoplasma gondii
journal contribution
posted on 2023-05-20, 00:34 authored by Ellis, J, Duncan SinclairDuncan Sinclair, Morrison, DMicroarray technology is emerging as a powerful method for the study of those changes in gene expression that occur when a parasite converts from one life cycle stage to another. The use of appropriate experimental design and data analysis methodologies is essential if this technology is to be correctly exploited. In this review, the study of stage conversion in the transformation of Toxoplasma gondii tachyzoites into bradyzoites is considered as an example of where the application of microarrays is revealing exciting new knowledge on underlying molecular mechanisms. The more general application of microarrays in parasitology is also discussed.
History
Publication title
Trends in ParasitologyVolume
20Issue
6Pagination
288-295ISSN
1471-4922Department/School
Wicking Dementia Research Education CentrePublisher
Elsevier Sci LtdPlace of publication
The Boulevard, Langford Lane, Kidlington, Oxford, England, Oxon, Ox5 1GbRights statement
Copyright 2004 Elsevier Ltd.Repository Status
- Restricted