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The role of epithelial-mesenchymal transition in chronic obstructive pulmonary disease

journal contribution
posted on 2023-05-23, 00:16 authored by Jo-Maree CourtneyJo-Maree Courtney, Spafford, PL
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality worldwide, and there is currently no treatment that can halt the progression of the disease. Over the last decade there has been increasing interest in the idea that epithelial-mesenchymal transition (EMT) may be active in COPD. Here we review the evidence for EMT in COPD as well as the current progress being made on understanding the drivers and mechanisms involved. Finally, we discuss the potential benefits that understanding EMT may bring to the field of chronic respiratory disease.

History

Publication title

Cells, Tissues, Organs

Volume

203

Pagination

99-104

ISSN

1422-6405

Department/School

Tasmanian School of Medicine

Publisher

Karger

Place of publication

Allschwilerstrasse 10, Basel, Switzerland, Ch-4009

Rights statement

© 2017 S. Karger AG, Basel

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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