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The role of epithelial-mesenchymal transition in chronic obstructive pulmonary disease
journal contribution
posted on 2023-05-23, 00:16 authored by Jo-Maree CourtneyJo-Maree Courtney, Spafford, PLChronic obstructive pulmonary disease (COPD) is a major cause of mortality worldwide, and there is currently no treatment that can halt the progression of the disease. Over the last decade there has been increasing interest in the idea that epithelial-mesenchymal transition (EMT) may be active in COPD. Here we review the evidence for EMT in COPD as well as the current progress being made on understanding the drivers and mechanisms involved. Finally, we discuss the potential benefits that understanding EMT may bring to the field of chronic respiratory disease.
History
Publication title
Cells, Tissues, OrgansVolume
203Pagination
99-104ISSN
1422-6405Department/School
Tasmanian School of MedicinePublisher
KargerPlace of publication
Allschwilerstrasse 10, Basel, Switzerland, Ch-4009Rights statement
© 2017 S. Karger AG, BaselRepository Status
- Restricted