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The effects of inactivation methods of Yersinia ruckeri on the efficacy of single dip vaccination in Atlantic salmon (Salmo salar)
journal contribution
posted on 2023-05-19, 18:08 authored by Nguyen, TD, Crosbie, PBB, Barbara NowakBarbara Nowak, Andrew BridleAndrew BridleYersinia ruckeri causes significant losses in farmed salmonids (Tobback et al., 2009) and is the causative agent of both enteric red mouth disease in rainbow trout in the Northern Hemisphere (Tobback et al., 2009) and yersiniosis in Atlantic salmon (Salmo salar) in the Southern Hemisphere (Carson & Wilson, 2009). The first commercial yersiniosis vaccine was licensed in 1976 as formalin-killed whole cells of Y. ruckeri (see Bridle, Koop, & Nowak, 2012). Formalin inactivation is most commonly used for commercial fish vaccine production (Sommerset, Krossøy, Biering, & Frost, 2005). Inactivation of bacteria by formalin influences the physicochemical characteristics of surface antigens and may reduce protective efficacy against pathogenic bacteria (Tu, Chu, Zhuang, & Lu, 2010).
History
Publication title
Journal of Fish DiseasesVolume
41Issue
7Pagination
1173-1176ISSN
0140-7775Department/School
Institute for Marine and Antarctic StudiesPublisher
Blackwell Publishing LtdPlace of publication
9600 Garsington Rd, Oxford, England, Oxon, Ox4 2DgRights statement
Copyright 2018 John Wiley & Sons LtdRepository Status
- Restricted