University of Tasmania
Browse

File(s) not publicly available

The Trace of Non-classical Biogenic Amines: A New Road to Addiction Recovery

journal contribution
posted on 2023-05-19, 11:18 authored by Canales, JJ
timulant abuse is prevalent according to recent global epidemiological studies. Research into treatment for problematic stimulant abuse has yet to find a suitable pharmacotherapeutic agent to assist with detoxification, withdrawal and relapse prevention. The newly discovered trace amine-associated receptor 1 (TAAR1) constitutes a novel receptor target for medication development with significant potential to treat the pathological changes produced by chronic drug exposure, especially stimulant abuse. Here, I briefly review evidence indicating that TAAR1 modulates the activity of the dopamine system and strongly influences the neurochemical and behavioral actions of psychomotor stimulants. The evidence discussed confirms the view that TAAR1 is a promising candidate receptor for the design of new effective addiction therapies.

History

Publication title

Journal of Addiction Research & Therapy

Volume

4

Issue

5

Pagination

1-3

ISSN

2155-6105

Department/School

School of Psychological Sciences

Publisher

Omics Publishing Group

Place of publication

United States

Repository Status

  • Restricted

Socio-economic Objectives

Public health (excl. specific population health) not elsewhere classified

Usage metrics

    University Of Tasmania

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC