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Microscale photolytic eluent generation for chromatography

conference contribution
posted on 2023-05-23, 12:31 authored by Potter, OG, Thomas, ME, Emily HilderEmily Hilder, Michael BreadmoreMichael Breadmore
This paper describes a new method for the generation of gradients for microscale chromatography based on the photolytic degradation of photosensitive reagents. An inert dissolved photochemical is placed in the eluent and irradiated by variable intensity LEDs to proportionately degrade the photochemical into simple chemical components, such as HCl, which can be used to create pH gradients which can be used to perform gradient separations of antipsychotics.

History

Publication title

Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

Pagination

1338-1339

ISBN

978-161839595-5

Department/School

School of Natural Sciences

Publisher

Chemical and Biological Microsystems Society

Place of publication

Washington DC, USA

Event title

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

Event Venue

Seattle Washington, USA

Date of Event (Start Date)

2011-10-02

Date of Event (End Date)

2011-10-06

Rights statement

Copyright 2011 Chemical and Biological Microsystems Society (CBMS)

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

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