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Microscale photolytic eluent generation for chromatography
conference contribution
posted on 2023-05-23, 12:31 authored by Potter, OG, Thomas, ME, Emily HilderEmily Hilder, Michael BreadmoreMichael BreadmoreThis paper describes a new method for the generation of gradients for microscale chromatography based on the photolytic degradation of photosensitive reagents. An inert dissolved photochemical is placed in the eluent and irradiated by variable intensity LEDs to proportionately degrade the photochemical into simple chemical components, such as HCl, which can be used to create pH gradients which can be used to perform gradient separations of antipsychotics.
History
Publication title
Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011Pagination
1338-1339ISBN
978-161839595-5Department/School
School of Natural SciencesPublisher
Chemical and Biological Microsystems SocietyPlace of publication
Washington DC, USAEvent title
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011Event Venue
Seattle Washington, USADate of Event (Start Date)
2011-10-02Date of Event (End Date)
2011-10-06Rights statement
Copyright 2011 Chemical and Biological Microsystems Society (CBMS)Repository Status
- Restricted