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Human metallothionein gene MT1L mRNA is present in several human tissues but is unlikely to produce a metallothionein protein

journal contribution
posted on 2023-05-16, 10:50 authored by Adele HollowayAdele Holloway, Fiona StennardFiona Stennard, Adrian WestAdrian West
A human MT gene from the functional locus on Chromosome 16, MT1L, is characterised and shown to produce mRNA in at least four human tissues. This gene is unlikely to produce a metallothionein protein because it contains a termination codon at position 26, by analogy to other human MT1 genes. MT1L cDNA is almost identical to another metallothionein cDNA clone reported recently, MT1(R), suggesting that either there are unmapped human metallothionein genes, or that MT1L is polymorphic.

History

Publication title

FEBS Letters

Volume

404

Pagination

41-44

ISSN

0014-5793

Department/School

Tasmanian School of Medicine

Publisher

Elsevier Science BV

Place of publication

Amsterdam

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the environmental sciences

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