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Cold plasma welding system for surgical skin closure: in vivo porcine feasibility assessment


Harats, M and Lam, A and Maller, M and Kornhaber, R and Haik, J, Cold plasma welding system for surgical skin closure: in vivo porcine feasibility assessment, Wounds, 28 pp. 1-9. ISSN 1943-2704 (2016) [Refereed Article]

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Copyright 2016 HMP Communications

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Background: Cold plasma skin welding is a novel technology that bonds skin edges through soldering without the use of synthetic materials or conventional wound approximation methods such as sutures, staples, or skin adhesives. The cold plasma welding system uses a biological solder applied to the edges of a skin incision, followed by the application of cold plasma energy. The objectives of this study were to assess the feasibility of a cold plasma welding system in approximating and fixating skin incisions compared with conventional methods and to evaluate and define optimal plasma welding parameters and histopathological tissue response in a porcine model.

Methods and Materials: The cold plasma welding system (BioWeld1 System, IonMed Ltd, Yokneam, Israel) was used on porcine skin incisions using variable energy parameters. Wound healing was compared macroscopically and histologically to incisions approximated with sutures.

Results: When compared to sutured skin closure, cold plasma welding in specific system parameters demonstrated comparable and favorable wound healing results histopathologically as well as macroscopically. No evidence of epidermal damage, thermal or otherwise, was encountered in the specified parameters. Notably, bleeding, infection, and wound dehiscence were not detected at incision sites. Skin incisions welded at extreme energy parameters presented second-degree burns.

Conclusion: Implementation of cold plasma welding has been shown to be feasible for skin closure. Initial in vivo results suggest cold plasma welding might provide equal, if not better, healing results than traditional methods of closure.

Item Details

Item Type:Refereed Article
Keywords:cold plasma welding, suture techniques, wound healing, wound closure, bovine serum albumin, tensile strength
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Surgery
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Injury prevention and control
UTAS Author:Kornhaber, R (Dr Rachel Kornhaber)
ID Code:111882
Year Published:2016
Deposited By:Health Sciences
Deposited On:2016-10-13
Last Modified:2018-02-07
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