Number of items: 11

Journal Article
Dyer, MS and Reale, LA and Lewis, KE and Walker, AK and Dickson, TC and Woodhouse, A and Blizzard, CA, Mislocalisation of TDP‐43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex, Journal of Neurochemistry, 157, (4) pp. 1300-1315. ISSN 0022-3042 (2020) [Refereed Article]
Lewis, KEA and Bennett, W and Blizzard, CL and West, AK and Chung, RS and Chuah, MI, The influence of metallothionein treatment and treadmill running exercise on disease onset and survival in SOD1G93A amyotrophic lateral sclerosis mice, European Journal of Neuroscience, 52, (4) pp. 3223-3241. ISSN 0953-816X (2020) [Refereed Article]
Jiang, T and Handley, EE and Brizuela, MD and Dawkins, E and Lewis, KE and Clark, RM and Dickson, TC and Blizzard, CA, Amyotrophic lateral sclerosis mutant TDP-43 may cause synaptic dysfunction through altered dendritic spine function, Disease Models & Mechanisms, 12, (5) Article dmm038109. ISSN 1754-8403 (2019) [Refereed Article]
Alrafiah, A and Karyka, E and Coldicott, I and Iremonger, K and Lewis, KE and Ning, K and Azzouz, M, Plastin 3 promotes motor neuron axonal growth and extends survival in a mouse model of spinal muscular atrophy, Molecular Therapy - Methods & Clinical Development, 9 pp. 81-89. ISSN 2329-0501 (2018) [Refereed Article]
Iannitti, T and Scarrott, JM and Likhite, S and Coldicott, IRP and Lewis, KE and Heath, PR and Higginbottom, A and Myszczynska, MA and Milo, M and Hautbergue, GM and Meyer, K and Kaspar, BK and Ferraiuolo, L and Shaw, PJ and Azzouz, M, Translating SOD1 gene silencing toward the clinic: a highly efficacious, off-target-free, and biomarker-supported strategy for fALS, Molecular Therapy - Nucleic Acids, 12 pp. 75-88. ISSN 2162-2531 (2018) [Refereed Article]
Walker, C and Herranz-Martin, S and Karyka, E and Liao, C and Lewis, K and Elsayed, W and Lukashchuk, V and Chiang, S-C and Ray, S and Mulcahy, PJ and Jurga, M and Tsagakis, I and Iannitti, T and Chandran, J and Coldicott, I and De Vos, KJ and Hassan, MK and Higginbottom, A and Shaw, PJ and Hautbergue, GM and Azzouz, M and El-Khamisy, SF, C9orf72 expansion disrupts ATM-mediated chromosomal break repair, Nature Neuroscience, 20, (9) pp. 1225-1235. ISSN 1097-6256 (2017) [Refereed Article]
Herranz-Martin, S and Chandran, J and Lewis, K and Mulcahy, P and Higginbottom, A and Walker, C and Valenzuela, IMY and Jones, RA and Coldicott, I and Iannitti, T and Akaaboune, M and El-Khamisy, SF and Gillingwater, TH and Shaw, PJ and Azzouz, M, Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits, Disease Models & Mechanisms, 10, (7) pp. 859-868. ISSN 1754-8403 (2017) [Refereed Article]
Lukashchuk, V and Lewis, KE and Coldicott, I and Grierson, AJ and Azzouz, M, AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice, Molecular Therapy - Methods & Clinical Development, 3 Article 15055. ISSN 2329-0501 (2016) [Refereed Article]
Blizzard, CA and Southam, KA and Dawkins, E and Lewis, KE and King, AE and Clark, JA and Dickson, TC, Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity, Disease Models & Mechanisms, 8, (3) pp. 215-224. ISSN 1754-8403 (2015) [Refereed Article]
Lewis, KE and Rasmussen, A and Bennett, W and King, A and West, AK and Chung, RS and Chuah, MI, Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: Changes in arginase1 and inducible nitric oxide synthase, Journal of Neuroinflammation, 11 Article 55. ISSN 1742-2094 (2014) [Refereed Article]
Lewis, KE and Chung, RS and West, AK and Chuah, MI, Distribution of exogenous metallothionein following intraperitoneal and intramuscular injection of metallothionein-deficient mice, Histology and histopathology, 27, (11) pp. 1459-1470. ISSN 0213-3911 (2012) [Refereed Article]

This list was generated on Sat Mar 25 18:21:31 2023.