Journal Article |
Khadka, S and Khan, S and Goldberg, LR and King, A and Bettiol, SS, Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review, Age and Ageing ISSN 0002-0729 (In Press) [Refereed Article] | |
Khadka, S and Khan, S and King, A and Goldberg, LR and Crocombe, L and Bettiol, S, Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review, Age and Ageing, 50, (1) pp. 80-87. ISSN 0002-0729 (2021) [Refereed Article] |  |
Ward, DD and Summers, MJ and Valenzuela, MJ and Srikanth, VK and Summers, JJ and King, AE and Ritchie, K and Robinson, AL and Vickers, JC, Associations of later-life education, the BDNF Val66Met polymorphism and cognitive change in older adults, The Journal of Prevention of Alzheimer's Disease, 7, (1) pp. 37-42. ISSN 2274-5807 (2020) [Refereed Article] | |
Ooi, L and Dottori, M and Cook, AL and Engel, M and Gautam, V and Grubman, A and Hernandez, D and King, AE and Maksour, S and Targa Dias Anastacio, H and Balez, R and Pebay, A and Pouton, C and Valenzuela, M and White, A and Williamson, R, from the Australian Dementia Stem Cell Consortium, If human brain organoids are the answer to understanding dementia, what are the questions?, The Neuroscientist, 26, (5-6) pp. 438-454. ISSN 1073-8584 (2020) [Refereed Article] |  |
Holloway, OG and King, AE and Ziebell, JM, Microglia demonstrate local mixed inflammation and a defined morphological shift in an APP/PS1 mouse model, Journal of Alzheimer's Disease, 77, (4) pp. 1765-1781. ISSN 1387-2877 (2020) [Refereed Article] |  |
Collins, JM and Woodhouse, A and Bye, N and Vickers, JC and King, AE and Ziebell, JM, Pathological links between traumatic brain injury and dementia: Australian pre-clinical research, Journal of Neurotrauma, 37, (5) pp. 782-791. ISSN 0897-7151 (2020) [Refereed Article] | |
Fulopova, B and Stuart, KE and Bennett, W and Bindoff, A and King, AE and Vickers, JC and Canty, AJ, Regional differences in beta amyloid plaque deposition and variable response to midlife environmental enrichment in the cortex of APP/PS1 mice, Journal of Comparative Neurology pp. 1-14. ISSN 0021-9967 (2020) [Refereed Article] |  |
Collins, JM and King, AE and Woodhouse, A and Kirkcaldie, MTK and Vickers, JC, Age moderates the effects of traumatic brain injury on beta-amyloid plaque load in APP/PS1 mice, Journal of Neurotrauma, 36, (11) pp. 1876-1889. ISSN 0897-7151 (2019) [Refereed Article] | |
Vickers, JC and King, AE and McCormack, GH and Bindoff, AD and Adlard, PA, Iron is increased in the brains of ageing mice lacking the neurofilament light gene, PLoS ONE, 14, (10) Article e0224169. ISSN 1932-6203 (2019) [Refereed Article] |  |
Stuart, KE and King, AE and King, NE and Collins, JM and Vickers, JC and Ziebell, JM, Late-life environmental enrichment preserves short-term memory and may attenuate microglia in male APP/PS1 mice, Neuroscience, 408 pp. 282-292. ISSN 0306-4522 (2019) [Refereed Article] | |
Tian, N and Hanson, KA and Canty, AJ and Vickers, JC and King, AE, Microtubule-dependent processes precede pathological calcium influx in excitotoxin-induced axon degeneration, Journal of Neurochemistry, 152, (5) pp. 542-555. ISSN 0022-3042 (2019) [Refereed Article] |  |
Holloway, OG and Canty, AJ and King, AE and Ziebell, JM, Rod microglia and their role in neurological diseases, Seminars in Cell and Developmental Biology, 94 pp. 96-103. ISSN 1084-9521 (2019) [Refereed Article] | |
Pietzuch, M and King, AE and Ward, DD and Vickers, JC, The influence of genetic factors and cognitive reserve on structural and functional resting-state brain networks in aging and Alzheimer's disease, Frontiers in Aging Neuroscience, 11 Article 30. ISSN 1663-4365 (2019) [Refereed Article] |  |
Li, F and Hung, SSC and Mohd Khalid, MKN and Wang, J-H and Chrysostomou, V and Wong, VHY and Singh, V and Wing, K and Tu, L and Bender, JA and Pebay, A and King, AE and Cook, AL and Wong, RCB and Bui, BV and Hewitt, AW and Liu, G-S, Utility of self-destructing CRISPR/Cas constructs for targeted gene editing in the retina, Human Gene Therapy, 30, (11) pp. 1349-1360. ISSN 1043-0342 (2019) [Refereed Article] | |
Tu, L and Wang, J-H and Barathi, VA and Prea, SM and He, Z and Lee, JH and Bender, J and King, AE and Logan, GJ and Alexander, IE and Bee, Y-S and Tai, M-H and Dusting, GJ and Bui, BV and Zhong, J and Liu, G-S, AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization, Angiogenesis, 21, (1) pp. 95-109. ISSN 0969-6970 (2018) [Refereed Article] | |
O'Mara, AR and Collins, JM and King, AE and Vickers, JC and Kirkcaldie, MTK, Accurate and unbiased quantitation of Amyloid-β fluorescence images using ImageSURF, Current Alzheimer Research, 16, (2) pp. 102-108. ISSN 1567-2050 (2018) [Refereed Article] | |
Chhetri, J and King, AE and Gueven, N, Alzheimer's Disease and NQO1: is there a link?, Current Alzheimer Research, 15 pp. 56-66. ISSN 1567-2050 (2018) [Refereed Article] | |
King, A and Brain, A and Hanson, K and Dittmann, J and Vickers, J and Fernandez-Martos, C, Disruption of leptin signalling in a mouse model of Alzheimer's disease, Metabolic Brain Disease, 33, (4) pp. 1097-1110. ISSN 0885-7490 (2018) [Refereed Article] | |
Woodhouse, A and Fernandez-Martos, CM and Atkinson, RAK and Hanson, KA and Collins, JM and O'Mara, AR and Terblanche, N and Skinner, MW and Vickers, JC and King, AE, Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice, BMC Anesthesiology, 18, (1) Article 47. ISSN 1471-2253 (2018) [Refereed Article] |  |
Hanson, K and Tian, N and Vickers, JC and King, AE, The HDAC6 inhibitor trichostatin a acetylates microtubules and protects axons from excitotoxin-induced degeneration in a compartmented culture model, Frontiers in Neuroscience, 12, (NOV) Article 872. ISSN 1662-453X (2018) [Refereed Article] |  |
Leung, JYK and Bennett, WR and King, AE and Chung, RS, The impact of metallothionein-II on microglial response to tumor necrosis factor-alpha (TNFα) and downstream effects on neuronal regeneration, Journal of Neuroinflammation, 15, (1) pp. 1-9. ISSN 1742-2094 (2018) [Refereed Article] |  |
Imlach, A and Ward, DD and Stuart, KE and Summers, MJ and Valenzuela, MJ and King, AE and Saunders, NL and Summers, J and Srikanth, VK and Robinson, A and Vickers, JC, Age is no barrier: predictors of academic success in older learners, npj Science of Learning, 2 Article 13. ISSN 2056-7936 (2017) [Refereed Article] |  |
Clark, RM and Blizzard, CA and Young, KM and King, AE and Dickson, TC, Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1G93A mouse model of ALS, Scientific Reports, 7 Article 44461. ISSN 2045-2322 (2017) [Refereed Article] |  |
Stuart, KE and King, AE and Fernandez-Martos, CM and Summers, MJ and Vickers, JC, Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer's model, Scientific Reports, 7, (1) Article 2764. ISSN 2045-2322 (2017) [Refereed Article] |  |
O'Mara, A and King, AE and Vickers, JC and Kirkcaldie, MTK, ImageSURF: An ImageJ plugin for batch pixel-based image segmentation using random forests, Journal of Open Research Software, 5 Article 31. ISSN 2049-9647 (2017) [Refereed Article] |  |
Stuart, KE and King, AE and Fernandez-Martos, CM and Dittmann, J and Summers, MJ and Vickers, JC, Mid-life environmental enrichment increases synaptic density in CA1 in a mouse model of Aβ-associated pathology and positively influences synaptic and cognitive health in healthy ageing, Journal of Comparative Neurology, 525, (8) pp. 1797-1810. ISSN 0021-9967 (2017) [Refereed Article] | |
Yap, YC and King, AE and Guijt, RM and Jiang, T and Blizzard, CA and Breadmore, MC and Dickson, TC, Mild and repetitive very mild axonal stretch injury triggers cystoskeletal mislocalization and growth cone collapse, PLoS One, 12, (5) Article e0176997. ISSN 1932-6203 (2017) [Refereed Article] |  |
Cui, H and King, AE and Jacobson, GA and Small, DH, Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice, Journal of Neuroscience Research, 95, (4) pp. 992-999. ISSN 0360-4012 (2017) [Refereed Article] | |
Hung, SSC and Chrysostomou, V and Li, F and Lim, JKH and Wang, J-H and Powell, JE and Tu, L and Daniszewski, M and Lo, C and Wong, RC and Crowston, JG and Pebay, A and King, AE and Bui, BV and Liu, G-S and Hewitt, AW, AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo, Investigative Ophthalmology & Visual Science, 57, (7) pp. 3470-3476. ISSN 1552-5783 (2016) [Refereed Article] |  |
Vickers, JC and Kirkcaldie, MT and Phipps, A and King, AE, Alterations in neurofilaments and the transformation of the cytoskeleton in axons may provide insight into the aberrant neuronal changes of Alzheimer's disease, Brain Research Bulletin, 126, (Pt 3) pp. 324-333. ISSN 0361-9230 (2016) [Refereed Article] | |
Gupta, VK and Chitranshi, N and Gupta, VB and Golzan, M and Dheer, Y and Wall, RV and Georgevsky, D and King, AE and Vickers, JC and Chung, R and Graham, S, Amyloid β accumulation and inner retinal degenerative changes in Alzheimer's disease transgenic mouse, Neuroscience Letters, 623 pp. 52-56. ISSN 0304-3940 (2016) [Refereed Article] | |
Clark, JA and Southam, KA and Blizzard, CA and King, AE and Dickson, TC, Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis, Journal of Chemical Neuroanatomy, 76, (Pt A) pp. 35-47. ISSN 0891-0618 (2016) [Refereed Article] | |
Fernandez-Martos, CM and Atkinson, RAK and Chuah, MI and King, AE and Vickers, JC, Combination treatment with leptin and pioglitazone in a mouse model of Alzheimer's disease, Alzheimer's & Dementia: Translational Research & Clinical Interventions, 3, (1) pp. 92-106. ISSN 2352-8737 (2016) [Refereed Article] |  |
Vickers, J and Mitew, S and Woodhouse, A and Fernandez-Martos, CM and Kirkcaldie, MT and Canty, AJ and McCormack, GH and King, AE, Defining the earliest pathological changes of Alzheimer's disease, Current Alzheimer research, 13, (3) pp. 281-287. ISSN 1567-2050 (2016) [Refereed Article] | |
King, AE and Woodhouse, A and Kirkcaldie, MTK and Vickers, JC, Excitotoxicity in ALS: Overstimulation, or overreaction?, Experimental Neurology, 275 pp. 162-171. ISSN 0014-4886 (2016) [Refereed Article] | |
Soo, KY and Sultana, J and King, AE and Atkinson, RAK and Warraich, ST and Sundaramoorthy, V and Blair, I and Farg, MA and Atkin, JD, ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1, Cell Death Discovery, 1 Article 15030. ISSN 2058-7716 (2015) [Refereed Article] |  |
Atkinson, RA and Fernandez-Martos, CM and Atkin, J and Vickers, JC and King, AE, C9ORF72 expression and cellular localization over mouse development, Acta neuropathologica communications, 3 Article 59. ISSN 2051-5960 (2015) [Refereed Article] |  |
Liu, Y and Atkinson, RAK and Fernandez-Martos, CM and Kirkcaldie, MTK and Cui, H and Vickers, JC and King, AE, Changes in TDP-43 expression in development, aging, and in the neurofilament light protein knockout mouse, Neurobiology of Aging: Experimental and Clinical Research, 36, (2) pp. 1151-1159. ISSN 0197-4580 (2015) [Refereed Article] | |
Franks, K and Chuah, MI and King, AE and Vickers, JC, Connectivity of pathology: the olfactory system as a model for network-driven mechanisms of Alzheimer's disease pathogenesis, Frontiers in Aging Neuroscience, 7 Article 234. ISSN 1663-4365 (2015) [Refereed Article] |  |
Blizzard, CA and Southam, KA and Dawkins, E and Lewis, KE and King, AE and Clark, JA and Dickson, TC, Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity, Disease Models & Mechanisms, 8, (3) pp. 215-224. ISSN 1754-8403 (2015) [Refereed Article] |  |
Fernandez-Martos, CM and King, AE and Atkinson, RAK and Woodhouse, A and Vickers, JC, Neurofilament light gene deletion exacerbates amyloid, dystrophic neurite, and synaptic pathology in the APP/PS1 transgenic model of Alzheimer's disease, Neurobiology of Aging, 36, (10) pp. 2757-2767. ISSN 0197-4580 (2015) [Refereed Article] | |
Soo, KY and Halloran, M and Sundaramoorthy, V and Parakh, S and Toth, RP and Southam, KA and McLean, CA and Lock, P and King, A and Farg, MA and Atkin, JD, Rab1-dependent ER-Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS, Acta Neuropathologica, 130, (5) pp. 679-697. ISSN 0001-6322 (2015) [Refereed Article] | |
Collins, JM and King, AE and Woodhouse, A and Kirkcaldie, MTK and Vickers, JC, The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease, Experimental Neurology, 267 pp. 219-29. ISSN 0014-4886 (2015) [Refereed Article] | |
Farg, MA and Sundaramoorthy, V and Sultana, JM and Yang, S and Atkinson, RAK and Levina, V and Halloran, MA and Gleeson, PA and Blair, IP and Soo, KY and King, AE and Atkin, JD, C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking, Human Molecular Genetics, 23, (13) Article ddu068. ISSN 0964-6906 (2014) [Refereed Article] |  |
Siedler, DG and Chuah, MI and Kirkcaldie, MTK and Vickers, JC and King, AE, Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments, Frontiers in Cellular Neuroscience, 8 Article 429. ISSN 1662-5102 (2014) [Refereed Article] |  |
Yap, YC and Dickson, TC and King, AE and Breadmore, MC and Guijt, RM, Microfluidic culture platform for studying neuronal response to mild to very mild axonal stretch injury, Biomicrofluidics, 8, (4) Article 044110. ISSN 1932-1058 (2014) [Refereed Article] |  |
Lewis, KE and Rasmussen, AL and Bennett, W and King, A and West, AK and Chung, RS and Chuah, MI, Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: Changes in arginase1 and inducible nitric oxide synthase, Journal of Neuroinflammation, 11 Article 55. ISSN 1742-2094 (2014) [Refereed Article] |  |
Musgrove, RE and Horne, H and Wilson, R and King, AE and Edwards, LM and Dickson, TC, The metabolomics of alpha-synuclein (SNCA) gene deletion and mutation in mouse brain, Metabolomics, 10, (1) pp. 114-122. ISSN 1573-3882 (2014) [Refereed Article] | |
Musgrove, RE and King, AE and Dickson, TC, α-Synuclein protects neurons from apoptosis downstream of free-radical production through modulation of the MAPK signalling pathway, Neurotoxicity Research, 23, (4) pp. 358-369. ISSN 1476-3524 (2013) [Refereed Article] | |
Blizzard, CA and King, AE and Vickers, J and Dickson, T, Cortical murine neurons lacking the neurofilament light chain protein have an attenuated response to injury in vitro, Journal of Neurotrauma, 30, (22) pp. 1908-1918. ISSN 0897-7151 (2013) [Refereed Article] | |
King, AE and Southam, KA and Dittmann, J and Vickers, JC, Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol, Acta Neuropathologica Communications, 1 Article 59. ISSN 2051-5960 (2013) [Refereed Article] |  |
Southam, KA and King, AE and Blizzard, CA and McCormack, GH and Dickson, TC, Microfluidic primary culture model of the lower motor neuron-neuromuscular junction circuit, Journal of Neuroscience Methods, 218, (2) pp. 164-169. ISSN 0165-0270 (2013) [Refereed Article] | |
Yap, YC and Guijt, RM and Dickson, TC and King, AE and Breadmore, MC, Stainless steel pinholes for fast fabrication of high-performance microchip electrophoresis devices by CO2 laser ablation, Analytical Chemistry, 85, (21) pp. 10051-10056. ISSN 0003-2700 (2013) [Refereed Article] | |
Hosie, KA and King, AE and Blizzard, CA and Vickers, JC and Dickson, TC, Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model, ASN Neuro, 4, (1) Article e00076. ISSN 1759-0914 (2012) [Refereed Article] |  |
Liu, Yao and Staal, JA and Canty, AJ and Kirkcaldie, MTK and King, AE and Bibari, O and Mitew, ST and Dickson, TC and Vickers, JC, Cytoskeletal changes during development and aging in the cortex of neurofilament light protein knockout mice, The Journal of Comparative Neurology, 521, (8) pp. 1817-1827. ISSN 0021-9967 (2012) [Refereed Article] | |
King, AE and Blizzard, CA and Southam, KA and Vickers, JC and Dickson, TC, Degeneration of axons in spinal white matter in G93A mSOD1 mouse characterized by NFL and alpha internexin immunoreactivity, Brain Research, 1465 pp. 90-100. ISSN 0006-8993 (2012) [Refereed Article] | |
Blizzard, CA and Chuckowree, JA and King, AE and Hosie, KA and McCormack, GH and Chapman, JA and Vickers, JC and Dickson, TC, Focal Damage to the Adult Rat Neocortex Induces Wound Healing Accompanied by Axonal Sprouting and Dendritic Structural Plasticity , Cerebral Cortex, 21, (2) pp. 281-291. ISSN 1047-3211 (2011) [Refereed Article] |  |
King, AE and Dickson, TC and Blizzard, CA and Woodhouse, A and Foster, SS and Chung, RS and Vickers, JC, Neuron-glia interactions underlie ALS-like axonal cytoskeletal pathology, Neurobiology of Aging: Experimental and Clinical Research, 32, (3) pp. 459-469. ISSN 0197-4580 (2011) [Refereed Article] |  |
Musgrove, RE and King, AE and Dickson, TC, Neuroprotective upregulation of endogenous alpha-synuclein precedes ubiquitination in cultured dopaminergic neurons , Neurotoxicity Research , 19, (4) pp. 592-602. ISSN 1029-8428 (2011) [Refereed Article] |  |
Blizzard, CA and King, AE and Haas, MA and O'Toole, DA and Vickers, JC and Dickson, TC, Axonal shearing in mature cortical neurons induces attempted regeneration and the reestablishment of neurite polarity, Brain Research: International Multidisciplinary Journal Devoted to Fundamental Research in The Brain Sciences, 1300, (November) pp. 24-36. ISSN 0006-8993 (2009) [Refereed Article] | |
Vickers, JC and King, AE and Woodhouse, A and Kirkcaldie, MT and Staal, JA and McCormack, GH and Blizzard, CA and Musgrove, RE and Mitew, S and Liu, Y and Chuckowree, JA and Bibari, O and Dickson, TC, Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system , Brain Research Bulletin, 80, (4-5) pp. 217-223. ISSN 0361-9230 (2009) [Refereed Article] | |
Woodhouse, A and Shepherd, CE and Sokolova, A and Carroll, VL and King, AE and Halliday, GM and Dickson, TC and Vickers, JC, Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease, Acta Neuropathologica, 117, (1) pp. 19-29. ISSN 0001-6322 (2009) [Refereed Article] | |
King, AE and Dickson, TC and Blizzard, CA and Foster, SS and Chung, RS and West, AK and Chuah, MI and Vickers, JC, Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons, European Journal of Neuroscience, 26, (8) pp. 2151-2159. ISSN 0953-816X (2007) [Refereed Article] | |
Quilty, MC and King, AE and Gai, WP and Pountney, DL and West, AK and Vickers, JC and Dickson, TC, Alpha-synuclein is upregulated in neurones in response to chronic oxidative stress and is associated with neuroprotection, Experimental Neurology, 199, (2) pp. 249-256. ISSN 0014-4886 (2006) [Refereed Article] | |
King, AE and Chung, RS and Vickers, JC and Dickson, TC, Localisation of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity, Journal of Comparative Neurology, 498, (2) pp. 277-294. ISSN 0021-9967 (2006) [Refereed Article] | |
King, AE and Bartlett, C and Sauve, Y and Lund, R and Dunlop, S and Beazley, L, Retinal ganglion cell axons regenerate in the presence of intact sensory fibres, Neuroreport, 17, (2) pp. 195-199. ISSN 0959-4965 (2006) [Refereed Article] | |
Chung, RS and McCormack, GH and King, AE and West, AK and Vickers, JC, Glutamate induces rapid loss of axonal neurofilament proteins from cortical neurons in vitro, Experimental Neurology, 193, (2) pp. 481-488. ISSN 0014-4886 (2005) [Refereed Article] | |