eCite Digital Repository

Author: Small, DH (Professor David Small)

Number of items: 127

Journal Article
Southam, KA and Stennard, F and Pavez, C and Small, DH, Knockout of amyloid β protein precursor (APP) expression alters synaptogenesis, neurite branching and axonal morphology of hippocampal neurons, Neurochemical Research pp. 1-10. ISSN 0364-3190 (2018) [Refereed Article] 
Cui, H and King, AE and Jacobson, GA and Small, DH, Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice, Journal of Neuroscience Research, 95, (4) pp. 992-999. ISSN 0360-4012 (2017) [Refereed Article] 
Southam, KA and Vincent, AJ and Small, DH, Do microglia default on network maintenance in Alzheimer's disease?, Journal of Alzheimer's Disease, 51, (3) pp. 657-669. ISSN 1387-2877 (2016) [Refereed Article]
Smith, AI and Rajapakse, NW and Kleifeld, O and Lomonte, B and Sikanyika, NL and Spicer, AJ and Hodgson, WC and Conroy, PJ and Small, DH and Kaye, DM and Parkington, HC and Whisstock, JC and Kuruppu, S, N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin, Scientific Reports, 6 Article 22413. ISSN 2045-2322 (2016) [Refereed Article]
Small, DH and Hu, Y and Bolos, M and Dawkins, E and Foa, L and Young, KM, β-Amyloid precursor protein: function in stem cell development and Alzheimer's disease brain, Neurodegenerative Diseases, 13, (2-3) pp. 96-98. ISSN 1660-2854 (2014) [Refereed Article] 
Dawkins, E and Small, DH, Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease, Journal of Neurochemistry, 129, (5) pp. 756-769. ISSN 0022-3042 (2014) [Refereed Article]
Bolos, M and Hu, Y and Young, KM and Foa, L and Small, DH, Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis, Journal of Biological Chemistry, 289, (45) pp. 31253-31261. ISSN 0021-9258 (2014) [Refereed Article] 
Dawkins, E and Gasperini, R and Hu, Y and Cui, H and Vincent, AJ and Bolos, M and Young, KM and Foa, L and Small, DH, The N-terminal fragment of the β-amyloid precursor protein of Alzheimer's disease (N-APP) binds to phosphoinositide-rich domains on the surface of hippocampal neurons, Journal of Neuroscience Research, 92, (11) pp. 1478-1489. ISSN 1097-4547 (2014) [Refereed Article] 
Cui, H and Freeman, C and Jacobson, GA and Small, DH, Proteoglycans in the central nervous system: Role in development, neural repair, and Alzheimer's disease, IUBMB Life, 65, (2) pp. 108-120. ISSN 1521-6543 (2013) [Refereed Article] 
Hu, Y and Hung, AC and Cui, H and Dawkins, E and Bolos, M and Foa, L and Young, KM and Small, DH, Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells, Journal of Biological Chemistry, 288, (26) pp. 18853-18862. ISSN 0021-9258 (2013) [Refereed Article]
Silveyra, M-X and Garcia-Ayllon, M-S and de Barreda, EG and Small, DH and Martinez, S and Avila, J and Saez-Valero, J, Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice, Neurobiology of Aging: Experimental and Clinical Research, 33, (3) pp. 624.e23- 624.e34. ISSN 0197-4580 (2012) [Refereed Article]
Zhai, J and Lee, TH and Small, DH and Aguilar, M-I, Characterization of early stage intermediates in the nucleation phase of Aβ aggregation, Biochemistry, 51, (6) pp. 1070-1078. ISSN 0006-2960 (2012) [Refereed Article] 
Small, DH, Dysregulation of Ca2+ homeostasis in Alzheimer's disease: role in acetylcholinesterase production and AMPA receptor internalization, Neurodegenerative Diseases, 10, (1-4) pp. 76-79. ISSN 1660-2854 (2012) [Refereed Article]
Gasperini, RJ and Small, DH, Neurodegeneration in Familal Amyloidotic Polyneuropathy, Clinical and Experimental Pharmacology and Physiology, 39, (8) pp. 680-683. ISSN 0305-1870 (2012) [Refereed Article]
Cui, H and Hung, AC and Freeman, C and Narkowicz, C and Jacobson, GA and Small, DH, Size and sulfation are critical for the effect of heparin on APP processing and A beta production, Journal of Neurochemistry, 123, (3) pp. 447-457. ISSN 0022-3042 (2012) [Refereed Article] 
Mitchell, CB and Gasperini, RJ and Small, DH and Foa, LC, STIM1 is necessary for store-operated calcium entry in turning growth cones, Journal of Neurochemistry, 122, (6) pp. 1155-66. ISSN 0022-3042 (2012) [Refereed Article] 
Small, DH and Aguilar, M-I, Targeting pre-mRNA splicing: a BACE-ic strategy for AD drug development?, Journal of Neurochemistry, 121, (5) pp. 695-696. ISSN 0022-3042 (2012) [Letter or Note in Journal]
Cui, H and Hung, AC and Klaver, DW and Suzuki, T and Freeman, C and Narkowicz, C and Jacobson, GA and Small, DH, Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice, PLoS One, 6, (7) Article e23007. ISSN 1932-6203 (2011) [Refereed Article]
Garcia-Ayllon, MS and Small, DH and Avila, J and Saez-Valero, J, Revisiting the role of acetylcholinesterase in Alzheimer's disease: cross-talk with P-tau and β-amyloid, Frontiers in Molecular Neuroscience, 4 Article 22. ISSN 1662-5099 (2011) [Refereed Article]
Hou, X and Small, DH and Aguilar, MI, Surface Plasmon Resonance Spectroscopy: A New Lead in Studying the Membrane Binding of Amyloidogenic Transthyretin, Methods in Molecular Biology, 752 pp. 215-228. ISSN 1064-3745 (2011) [Refereed Article]
Gasperini, RJ and Hou, X and Parkington, H and Coleman, H and Klaver, DW and Vincent, AJ and Foa, LC and Small, DH, TRPM8 and Nav 1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons, Molecular Neurodegeneration, 6, (19) pp. 1-12. ISSN 1750-1326 (2011) [Refereed Article]
Liu, SJ and Gasperini, R and Foa, L and Small, DH, Amyloid-beta Decreases Cell-Surface AMPA Receptors by Increasing Intracellular Calcium and Phosphorylation of GluR2, Journal of Alzheimer's Disease, 21, (2) pp. 655-666. ISSN 1387-2877 (2010) [Refereed Article]
Vincent, AJ and Gasperini, R and Foa, L and Small, DH, Astrocytes in Alzheimer's Disease: Emerging Roles in Calcium Dysregulation and Synaptic Plasticity, Journal of Alzheimer's Disease, 22, (3) pp. 699-714. ISSN 1387-2877 (2010) [Refereed Article]
Klaver, D and Hung, AC and Gasperini, R and Foa, L and Aguilar, MI and Small, DH, Effect of Heparin on APP Metabolism and Aβ Production in Cortical Neurons, Neurodegenerative Diseases, 7, (1-3) pp. 187-189. ISSN 1660-2854 (2010) [Refereed Article]
Klaver, DW and Wilce, MCJ and Gasperini, R and Freeman, C and Juliano, JP and Parish, C and Foa, L and Aguilar, MI and Small, DH, Glycosaminoglycan-induced activation of the β-secretase (BACE1) of Alzheimer's disease, Journal of Neurochemistry, 112, (6) pp. 1552-1561. ISSN 0022-3042 (2010) [Refereed Article]
Kerr, ML and Gasperini, R and Gibbs, ME and Hou, X and Shepherd, CE and Strickland, DK and Foa, L and Lawen, A and Small, DH, Inhibition of Aβ aggregation and neurotoxicity by the 39-kDa receptor-associated protein, Journal of Neurochemistry, 112, (5) pp. 1199-1209. ISSN 0022-3042 (2010) [Refereed Article]
Klaver, DW and Wilce, MCJ and Cui, H and Hung, AC and Gasperini, R and Foa, L and Small, DH, Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions, Biological Chemistry: Official Journal of The German Society for Biochemistry and Molecular Biology, 391, (8) pp. 849-859. ISSN 1431-6730 (2010) [Refereed Article]
Small, DH and Klaver, DW and Foa, L, Presenilins and the gamma-secretase: still a complex problem, Molecular Brain, 3, (1) pp. 1-6. ISSN 1756-6606 (2010) [Refereed Article]
Beckman, M and Freeman, C and Parish, CR and Small, DH, Activation of cathepsin D by glycosaminoglycans, The F E B S Journal, 276, (24) pp. 7343-7352. ISSN 1742-464X (2009) [Refereed Article] 
Small, DH, Dysregulation of Calcium Homeostasis in Alzheimer's Disease, Neurochemical Research, 34, (10) pp. 1824-1829. ISSN 0364-3190 (2009) [Refereed Article] 
Small, DH and Gasperini, R and Vincent, AJ and Hung, AC and Foa, L, The Role of Aβ-Induced Calcium Dysregulation in the Pathogenesis of Alzheimer's Disease, Journal of Alzheimer's Disease, 16, (2) pp. 225-233. ISSN 1387-2877 (2009) [Refereed Article] 
Hou, X and Mechler, A and Martin, LL and Aguilar, MI and Small, DH, Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes, Biochimica et Biophysica Acta, 1778, (1) pp. 198-205. ISSN 0005-2736 (2008) [Refereed Article] 
Azari, MF and Ozturk, E and Profyris, C and Wang, S and Small, DH and Bernard, CC and Petratos, S, LIF treatment reduces Nogo-A deposits in spinal cord injury modulating Rho GTPase activity and CRMP-2 phosphorylation, Journal of Neurodegeneration and Regeneration, 1, (1) pp. 23-29. ISSN 1932-1481 (2008) [Refereed Article] 
Gibbs, ME and Maksel, D and Gibbs, Z and Hou, X and Summers, RJ and Small, DH, Memory loss caused by s-amyloid protein is rescued by as3-adrenoceptor agonist, Neurobiology of Aging, 31, (4) EJ ISSN 0197-4580 (2008) [Refereed Article] 
Petratos, S and Li, QX and George, AJ and Hou, X and Kerr, ML and Unabia, SE and Hatzinisiriou, I and Maksel, D and Aguilar, MI and Small, DH, The beta-amyloid protein of Alzheimers disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism, Brain, 131, (1) pp. 90-108. ISSN 0006-8950 (2008) [Refereed Article] 
Small, DH, Neural Network Dysfunction in Alzheimer's Disease: A Drug Development Perspective, Drug News and Perspectives: The International Drug Newsmagazine, 20, (9) pp. 557-563. ISSN 0214-0934 (2007) [Refereed Article] 
Small, DH and Maksel, D and Kerr, ML and Ng, J and Hou, X and Chu, C and Mehrani, H and Unabia, S and Azari, MF and Loiacono, R and Aguilar, MI and Chebib, M, The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor, Journal of Neurochemistry, 101, (6) pp. 1527-1538. ISSN 0022-3042 (2007) [Refereed Article] 
Hou, X and Aguilar, MI and Small, DH, Transthyretin and familial amyloidotic polyneuropathy: Recent progress in understanding the molecular mechanism of neurodegeneration, The F E B S Journal, 274, (7) pp. 1637-1650. ISSN 1742-464X (2007) [Refereed Article] 
Hou, X and Parkington, HC and Coleman, HA and Mechler, A and Martin, LL and Aguilar, MI and Small, DH, Transthyretin oligomers induce calcium influx via voltage-gated calcium channels, Journal of Neurochemistry, 100, (2) pp. 446-457. ISSN 0022-3042 (2007) [Refereed Article] 
Losic, D and Martin, LL and Aguilar, MI and Small, DH, β-amyloid fibril formation is promoted by step edges of highly oriented pyrolytic graphite, Biopolymers: Original Research on Biological Molecules and Assemblies, 84, (5) pp. 519-526. ISSN 0006-3525 (2006) [Refereed Article] 
Small, DH and Cappai, R, Alois Alzheimer and Alzheimer's disease: a centennial perspective, Journal of Neurochemistry, 99, (3) pp. 708-710. ISSN 0022-3042 (2006) [Refereed Article]
Beckman, M and Holsinger, RMD and Small, DH, Heparin Activates β-Secretase (BACE1) of Alzheimer's Disease and Increases Autocatalysis of the Enzyme, Biochemistry, 45, (21) pp. 6703-6714. ISSN 0006-2960 (2006) [Refereed Article] 
Losic, D and Martin, LL and Mechler, A and Aguilar, MI and Small, DH, High resolution scanning tunnelling microscopy of the β-amyloid protein (Aβ1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly, Journal of Structural Biology, 155, (1) pp. 104-110. ISSN 1047-8477 (2006) [Refereed Article] 
Azari, MF and Profyris, C and Small, DH and Karnezis, T and Bernard, CC, Leukemia Inhibitory Factor Arrests Oligodendrocyte Death and Demyelination in Spinal Cord Injury, Journal of Neuropathology and Experimental Neurology, 65, (9) pp. 914-929. ISSN 0022-3069 (2006) [Refereed Article] 
Mok, SS and Losic, D and Barrow, CJ and Turner, BJ and Masters, CL and Martin, LL and Small, DH, The β-amyloid peptide of Alzheimer's disease decreases adhesion of vascular smooth muscle cells to the basement membrane, Journal of Neurochemistry, 96, (1) pp. 53-64. ISSN 0022-3042 (2006) [Refereed Article] 
Small, DH, Acetylcholinesterase inhibitors for the treatment of dementia in Alzheimer's disease: do we need new inhibitors?, Expert Opinion on Emerging Drugs, 10, (4) pp. 817-825. ISSN 1744-7623 (2005) [Refereed Article] 
Hou, X and Richardson, SJ and Aguilar, MI and Small, DH, Binding of Amyloidogenic Transthyretin to the Plasma Membrane Alters Membrane Fluidity and Induces Neurotoxicity, Biochemistry, 44, (30) pp. 11618-11627. ISSN 0006-2960 (2005) [Refereed Article] 
Small, DH, Biochemical, Cellular and Behavioural Aspects of Neurodegeneration: the View from Down Under, Neurotoxicity Research: An International Journal on Processes and Mechanisms in Neurodegeneration, Apoptosis, Neuroprotection and Regeneration, 7, (1-2) pp. 1-3. ISSN 1029-8428 (2005) [Contribution to Refereed Journal] 
Kerr, ML and Small, DH, Cytoplasmic Domain of the â-Amyloid Protein Precursor of Alzheimer's Disease: Function, Regulation of Proteolysis, and Implications for Drug Development, Journal of Neuroscience Research, 80, (2) pp. 151-159. ISSN 0360-4012 (2005) [Refereed Article]
Aguilar, MI and Small, DH, Surface Plasmon Resonance for the Analysis of β-Amyloid Interactions and Fibril Formation in Alzheimer's Disease Research, Neurotoxicity Research: An International Journal on Processes and Mechanisms in Neurodegeneration, Apoptosis, Neuroprotection and Regeneration, 7, (1-2) pp. 17-27. ISSN 1029-8428 (2005) [Refereed Article] 
Fodero, LR and Mok, SS and Losic, D and Martin, LL and Aguilar, MI and Barrow, CJ and Livett, BG and Small, DH, α7-nicotinic acetylcholine receptors mediate an Aβ1-42-induced increase in the level of acetylcholinesterase in primary cortical neurons, Journal of Neurochemistry, 88, (5) pp. 1186-1193. ISSN 0022-3042 (2004) [Refereed Article] 
Small, DH and Losic, D and Martin, LL and Turner, BJ and Freidhuber, A and Aguilar, MI, Alzheimer's disease therapeutics: new approaches to an ageing problem, I U B M B Life: (International Union of Biochemistry and Molecular Biology), 56, (4) pp. 203-208. ISSN 1521-6543 (2004) [Refereed Article] 
Small, DH, Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?, Trends in Neurosciences, 27, (5) pp. 245-249. ISSN 0166-2236 (2004) [Refereed Article] 
Small, DH, Mechanisms of synaptic homeostasis in Alzheimer's disease, Current Alzheimer Research, 1, (1) pp. 27-32. ISSN 1567-2050 (2004) [Refereed Article] 
Klug, GM and Losic, D and Subasinghe, SS and Aguilar, MI and Martin, LL and Small, DH, β Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH, The FEBS Journal, 270, (21) pp. 4282-4293. ISSN 1742-464X (2003) [Refereed Article] 
Saez-Valero, J and Fodero, LR and White, AR and Barrow, CJ and Small, DH, Acetycholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with β-amyloid peptides, Brain Research: International Multidisciplinary Journal Devoted to Fundamental Research in The Brain Sciences, 965, (1-2) pp. 283-286. ISSN 0006-8993 (2003) [Refereed Article] 
Subasinghe, S and Unabia, S and Barrow, CJ and Mok, SS and Aguilar, MI and Small, DH, Cholesterol is necessary both for the toxic effect of Aβ peptides on vascular smooth muscle cells and for Aβ binding to vascular smooth muscle cell membranes, Journal of Neurochemistry, 84, (3) pp. 471-479. ISSN 0022-3042 (2003) [Refereed Article] 
Saez-Valero, J and Fodero, LR and Sjogren, M and Andreasen, N and Amici, S and Gallai, V and Vanderstichele, H and Vanmechelen, E and Parnetti, L and Blennow, K and Small, DH, Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease, Journal of Neuroscience Research, 72, (4) pp. 520-526. ISSN 0360-4012 (2003) [Refereed Article] 
Small, DH and Smith, AI, Proteases and proteolytic processing in the nervous system: key targets for drug development, Journal of Neuroscience Research, 74, (3) pp. 339-341. ISSN 0360-4012 (2003) [Contribution to Refereed Journal] 
Nunan, J and Williamson, NA and Hill, AF and Sernee, MF and Masters, CL and Small, DH, Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease β-amyloid protein precursor: effect of C-terminal truncation on the production of β-amyloid protein, Journal of Neuroscience Research, 74, (3) pp. 378-385. ISSN 0360-4012 (2003) [Refereed Article] 
Fodero, LR and Saez-Valero, J and McLean, CA and Martins, RN and Beyreuther, K and Masters, CL and Robertson, TA and Small, DH, Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition, Journal of Neurochemistry , 81, (3) pp. 441-448. ISSN 0022-3042 (2002) [Refereed Article]
Mok, SS and Turner, BJ and Beyreuther, K and Masters, CL and Barrow, CJ and Small, DH, Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine, European Journal of Biochemistry: The Febs Journal, 269, (12) pp. 3014-3022. ISSN 0014-2956 (2002) [Refereed Article]
Saez-Valero, J and Small, DH, Acetylcholinesterase and butyrylcholinesterase glycoforms are biomarkers of Alzheimer's disease, Journal of Alzheimer's Disease, 3, (3) pp. 323-328. ISSN 1387-2877 (2001) [Refereed Article] 
Saez-Valero, J and Small, DH, Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease, Brain Research, 889, (1-2) pp. 247-250. ISSN 0006-8993 (2001) [Refereed Article]
Small, DH and Mok, SS and Bornstein, JC, Alzheimer's disease and Aβ toxicity: from top to bottom, Nature Reviews Neuroscience, 2 pp. 595-598. ISSN 1471-003X (2001) [Refereed Article] 
Saez-Valero, J and Mok, SS and Small, DH, An unusually glycosylated form of acetylcholinesterase is a CSF biomarker for Alzheimer's disease, Acta Neurologica Scandinavica. Supplementum, 176 pp. 49-52 . ISSN 0065-1427 (2001) [Refereed Article]
Nunan, J and Shearman, MS and Checler, F and Cappai, R and Evin, G and Beyreuther, K and Masters, CL and Small, DH, The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase, European Journal of Biochemistry: The Febs Journal, 268, (20) pp. 5329-5336. ISSN 0014-2956 (2001) [Refereed Article]
Fodero, LR and Saez-Valero, J and Barquero, MS and Marcos, A and McLean, CA and Small, DH, Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid, Journal of Neurochemistry, 79, (5) pp. 1022-1026. ISSN 0022-3042 (2001) [Refereed Article]
Saez-Valero, J and Barquero, MS and Marcos, A and McLean, CA and Small, DH, Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease, Journal of Neurology, Neurosurgery and Psychiatry, 69, (5) pp. 664-667. ISSN 0022-3050 (2000) [Refereed Article] 
Postuma, RB and He, WL and Nunan, J and Beyreuther, K and Masters, CL and Barrow, CJ and Small, DH, Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures, Journal of Neurochemistry, 74, (3) pp. 1122-1130. ISSN 0022-3042 (2000) [Refereed Article]
Yang, DS and Small, DH and Seydel, U and Smith, JD and Hallmayer, J and Gandy, SE and Martins, RN, Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner, Neuroscience: An International Journal, 90, (4) pp. 1217-1226. ISSN 0306-4522 (1999) [Refereed Article]
Saez-Valero, J and Sberna, G and McLean, CA and Small, DH, Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease, Journal of Neurochemistry, 72, (4) pp. 1600-1608. ISSN 0022-3042 (1999) [Refereed Article]
Cappai, R and Mok, SS and Galatis, D and Tucker, DF and Henry, A and Beyreuther, K and Small, DH and Masters, CL, Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth, F E B S Letters: (Federation of European Biochemical Societies), 442, (1) pp. 95-98. ISSN 0014-5793 (1999) [Refereed Article]
Caswell, MD and San Mok, S and Henry, A and Cappai, R and Klug, G and Beyreuther, K and Masters, CL and Small, DH, The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons, European Journal of Biochemistry: The Febs Journal, 266, (2) pp. 509-516. ISSN 0014-2956 (1999) [Refereed Article]
Sberna, G and Saez-Valero, J and Li, QX and Czech, C and Beyreuther, K and Masters, CL and McLean, CA and Small, DH, Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease, Journal of Neurochemistry, 71, (2) pp. 723-731. ISSN 0022-3042 (1998) [Refereed Article]
Postuma, RB and Martins, RN and Cappai, R and Beyreuther, K and Masters, CL and Strickland, DK and Mok, SS and Small, DH, Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture, F E B S Letters: (Federation of European Biochemical Societies), 428, (1-2) pp. 13-16. ISSN 0014-5793 (1998) [Refereed Article]
Moir, RD and Lynch, T and Bush, AI and Whyte, S and Henry, A and Portbury, S and Multhaup, G and Small, DH and Tanzi, RE and Beyreuther, K and Masters, CL, Relative increase in Alzheimer's disease of soluble forms of cerebral A beta amyloid protein precursor containing the Kunitz protease inhibitory domain, Journal of Biological Chemistry, 273, (9) pp. 5013-5019. ISSN 0021-9258 (1998) [Refereed Article]
Mok, SS and Evin, G and Li, QX and Smith, AI and Beyreuther, K and Masters, CL and Small, DH, A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments, Biochemistry, 36, (1) pp. 156-163. ISSN 0006-2960 (1997) [Refereed Article] 
Mok, SS and Sberna, G and Heffernan, D and Cappai, R and Galatis, D and Clarris, HJ and Sawyer, WH and Beyreuther, K and Masters, CL and Small, DH, Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease, F E B S Letters: (Federation of European Biochemical Societies), 415, (3) pp. 303-307. ISSN 0014-5793 (1997) [Refereed Article]
Saez-Valero, J and Sberna, G and McLean, CA and Masters, CL and Small, DH, Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease, The Lancet, 350 pp. 929. ISSN 0140-6736 (1997) [Letter or Note in Journal] 
Clarris, HJ and Cappai, R and Heffernan, D and Beyreuther, K and Masters, CL and Small, DH, Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping, Journal of Neurochemistry, 68, (3) pp. 1164-1172. ISSN 0022-3042 (1997) [Refereed Article]
Sberna, G and Saez-Valero, J and Beyreuther, K and Masters, CL and Small, DH, The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells, Journal of Neurochemistry, 69, (3) pp. 1177-1184. ISSN 0022-3042 (1997) [Refereed Article]
Williamson, TG and Mok, SS and Henry, A and Cappai, R and Lander, AD and Nurcombe, V and Beyreuther, K and Masters, CL and Small, DH, Secreted Glypican Binds to the Amyloid Precursor Protein of Alzheimer's Disease (APP) and Inhibits APP-induced Neurite Outgrowth, Journal of Biological Chemistry, 271, (49) pp. 31215-31221. ISSN 0021-9258 (1996) [Refereed Article] 
Small, DH, A function for butyrylcholinesterase, Journal of Neurochemistry , 64, (1) pp. 466-467. ISSN 0022-3042 (1995) [Letter or Note in Journal] 
Williamson, TG and Nurcombe, V and Beyreuther, K and Masters, CL and Small, DH, Affinity Purification of Proteoglycans that bind to the Amyloid Protein Precursor of Alzheimers Disease, Journal of Neurochemistry, 65, (5) pp. 2201-2208. ISSN 0022-3042 (1995) [Refereed Article]
Evin, G and Cappai, R and Li, QX and Culvenor, JG and Small, DH and Beyreuther, K and Masters, CL, Candidate Gamma-Secretases in the Generation of the Carboxyl-Terminus of the Alzheimers-Disease Beta-A4 Amyloid - Possible Involvement Of Cathepsin-D, Biochemistry, 34, (43) pp. 14185-14192. ISSN 0006-2960 (1995) [Refereed Article] 
Small, DH and Reed, G and Whitefield, B and Nurcombe, V, Cholinergic Regulation of Neurite Outgrowth from Isolated Chick Sympathetic Neurons in Culture, Journal of Neuroscience, 15, (1) pp. 144-151. ISSN 0270-6474 (1995) [Refereed Article] 
LePage, RN and Fosang, AJ and Fuller, SJ and Murphy, G and Evin, G and Beyreuther, K and Masters, CL and Small, DH, Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease, F E B S Letters: (Federation of European Biochemical Societies), 377, (2) pp. 267-270. ISSN 0014-5793 (1995) [Refereed Article]
Brickman, YG and Ford, MD and Small, DH and Bartlett, PF and Nurcombe, V, Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells, Journal of Biological Chemistry, 270, (42) pp. 24941-24948. ISSN 0021-9258 (1995) [Refereed Article]
Li, QX and Evin, G and Small, DH and Multhaup, G and Beyreuther, K and Masters, CL, Proteolytic Processing of Alzheimers-Disease Beta-A4 Amyloid Precursor Protein in Human Platelets, Journal of Biological Chemistry, 270, (23) pp. 14140-14147. ISSN 0021-9258 (1995) [Refereed Article]
Small, DH and Nurcombe, V and Reed, G and Clarris, H and Moir, R and Beyreuther, K and Masters, CL, A Heparin-binding Domain in the Amyloid Protein Precursor of Alzheimer's Disease Is Involved in the Regulation of Neurite Outgrowth, Journal of Neuroscience, 14, (4) pp. 2117-2127. ISSN 0270-6474 (1994) [Refereed Article] 
Bush, AI and Multhaup, G and Moir, RD and Williamson, TG and Small, DH and Rumble, B and Pollwein, P and Beyreuther, K and Masters, CL, A novel zinc(II) binding site modulates the function of the beta-A4 amyloid protein precursor of Alzheimer's disease, Journal of Biological Chemistry, 268, (22) pp. 16109-16112. ISSN 0021-9258 (1993) [Refereed Article]
Cheung, NS and Small, DH and Livett, BG, An amyloid peptide beta-A4 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells, Journal of Neurochemistry, 60, (3) pp. 1163-1166. ISSN 0022-3042 (1993) [Refereed Article]
Bush, AI and Whyte, S and Thomas, LD and Williamson, TG and Van Tiggelen, CV and Currie, J and Small, DH and Moir, RD and Li, QX and Rumble, B and Monning, U and Beyreuther, K and Masters, CL, An abnormality of plasma amyloid protein precursor in Alzheimer's disease, Annals of Neurology, 32, (1) pp. 57-65. ISSN 0364-5134 (1992) [Refereed Article]
Small, DH and Nurcombe, V and Moir, R and Michaelson, S and Monard, D and Beyreuther, K and Masters, CL, Association and Release of the Amyloid Protein Precursor of Alzheimer's Disease from Chick Brain Extracellular Matrix, Journal of Neuroscience, 12, (11) pp. 4143-4150. ISSN 0270-6474 (1992) [Refereed Article] 
Moir, RD and Martins, RN and Small, DH and Bush, AI and Milward, EA and Multhaup, G and Beyreuther, K and Masters, CL, Human brain beta-A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization. , Journal of Neurochemistry, 59, (4) pp. 1490-1498. ISSN 0022-3042 (1992) [Refereed Article]
Milward, EA and Papadopoulos, R and Fuller, SJ and Moir, RD and Small, D and Beyreuther, K and Masters, CL, The Amyloid Protein Precursor of Alzheimer's Disease Is a Mediator of the Effects of Nerve Growth Factor on Neurite Outgrowth, Neuron, 9 pp. 129-137. ISSN 0896-6273 (1992) [Refereed Article] 
Small, DH and Moir, RD and Fuller, S and Michaelson, S and Bush, AI and Li, QX and Milward, E and Hilbich, C and Weidemann, A and Beyreuther, K and Masters, CL, A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease, Biochemistry, 30, (44) pp. 10795-10799. ISSN 0006-2960 (1991) [Refereed Article] 
Kecorius, E and Small, DH and Livett, BG, Characterization of a dipeptidyl aminopeptidase from bovine adrenal medulla, Journal of Neurochemistry, 50, (1) pp. 38-44 . ISSN 0022-3042 (1988) [Refereed Article]
Small, DH and Chubb, IW, Identification of a trypsin-like site associated with acetylcholinesterase by affinity labelling with [H-3] diisopropyl fluorophosphate, Journal of Neurochemistry, 51, (1) pp. 69-74. ISSN 0022-3042 (1988) [Refereed Article]
Small, DH and Wurtman, RJ, Association of serotonin, dopamine, or noradrenaline with an actin-like component in pheochromocytoma (PC12) cells, Journal of Neurochemistry, 45, (3) pp. 825-831. ISSN 0022-3042 (1985) [Refereed Article]
Small, DH and Wurtman, RJ, Binding of [H-3] serotonin to skeletal muscle actin, Journal of Neurochemistry, 45, (3) pp. 819-824. ISSN 0022-3042 (1985) [Refereed Article]
Small, DH and Wurtman, RJ, Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes, National Academy of Sciences of The United States of America. Proceedings, 81, (3) pp. 959-963. ISSN 0027-8424 (1984) [Refereed Article]
Small, DH and Carnegie, PR, In Vivo Methylation of an Arginine in Chicken Myelin Basic Protein, Journal of Neurochemistry, 38, (1) pp. 184-190. ISSN 0022-3042 (1982) [Refereed Article]
Chapter in Book
Aguilar, M-I and Hou, X and Losic, D and Mechler, AI and Martin, LL and Small, DH, Single-Molecule Imaging of Amyloid-β Protein (Aβ) of Alzheimer's Disease: From Single-Molecule Structures to Aggregation Mechanisms and Membrane Interactions, Bio-nanoimaging: Protein Misfolding & Aggregation, Elsevier, Uversky VN and Lyubchenko YL (ed), United States of America, pp. 47-56. ISBN 978-0-12-394431-3 (2014) [Research Book Chapter] 
Gasperini, RJ and Klaver, DW and Hou, X and Aguilar, MI and Small, DH, Mechanisms of Transthyretin Aggregation and Toxicity, Protein Aggregation and Fibrillogenesis in Cerebral and Systematic Amyloid Disease, Subcellular Biochemistry 65, Springer, JR Harris (ed), Dordrecht, pp. 211-224. ISBN 978-94-007-5415-7 (2012) [Research Book Chapter] 
Hou, X and Small, DH and Aguilar, MI, Surface Plasmon Resonance Spectroscopy in Determination of the Interactions Between Amyloid β Proteins (Aβ) and Lipid Membranes , Methods in Molecular Biology: Surface Plasmon Resonance, Humana Press, NJ de Mol and MJE Fischer (ed), New York, pp. 225-235. ISBN 978-1-60761-669-6 (2010) [Other Book Chapter] 
Small, DH and Barrow, CJ, A Brief Introduction to the History of the β-Amyloid Protein of Alzheimer's Disease, Abeta Peptide and Alzheimer's Disease, Springer, C.J Barrow & D.H Small (ed), London, pp. 1-4. ISBN 978-1-85233-961-6 (2007) [Research Book Chapter] 
Ng, J and Aguilar, MI and Small, DH, Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer's Disease, Abeta Peptide and Alzheimer's Disease - Celebrating a Century of Research, Springer, Barrow CJ and Small DH (ed), London, pp. 93-101. ISBN 978-1-85233-961-6 (2007) [Research Book Chapter] 
Review
Small, DH, Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?, Trends in Molecular Medicine, 14, (3) pp. 103-108. (2008) [Substantial Review] 
Small, DH and Klaver, DW and Beckman, M, Regulation of proBACE1 by glycosaminoglycans, Neurodegenerative Diseases, 5, (3-4) pp. 206-208. (2008) [Review Several Works] 
Small, DH and Carnegie, PR, Myelopathy associated with vitamin B12 deficiency - new approaches to an old problem, Trends in Neuroscience, 4 pp. X-XI. (1981) [Review Several Works] 
Conference Publication
Bolos, M and Hu, Y and Foa, L and Young, KM and Small, DH, APP regulates neural stem or progenitor cell differentiation through neurogenin 2 expresssion, Federation of European Neuroscience Societies, 5-9 July, Milan, Italy (2014) [Conference Extract]
Hu, Y and Bolos, M and Dawkins, E and Foa, L and Young, K and Small, D, Cystatin C regulates neural stem or progenitor cell proliferation (Poster), 34th Annual Meeting Australasian Neuroscience Society, January, Adelaide, Australia (2014) [Conference Extract]
Bolos, M and Hu, Y and Foa, L and Young, K and Small, D, The role of Neurogenin2 in APP-stimulated neural stem or progenitor cell differentiation, 34th Annual Meeting Australasian Neuroscience Society, January, Adelaide, Australia (2014) [Conference Extract]
Dawkins, E and Vincent, AJ and Gasperini, R and Cui, H and Young, K and Foa, L and Small, DH, A direct interaction of Aβ with anionic cellular lipids mediates binding to neurons (Poster), 12th International Conference on Alzheimer's and Parkinson's Diseases, Florence, Italy (2013) [Conference Extract]
Hu, Y and Hung, AC and Cui, H and Dawkins, E and Foa, L and Young, KM and Small, DH, APP stimulates neural stem/progenitor cell proliferation by increasing cystatin C secretion. (Poster), 33rd Annual Meeting Australian Neuroscience Society, January, Melbourne, Australia (2013) [Conference Extract]
Dawkins, EA and Gasperini, R and Vincent, AJ and Foa, LC and Small, DH, Analysis of Aβ cell interactions and uptake in hippocampal culture, Proceedings of the 32nd Annual Meeting of the Australian Neuroscience Society, 29 January - 1 February 2012, Gold Coast, Australia, pp. 34. (2012) [Conference Extract]
Cui, H and Hung, AC and Narkowicz, CK and Jacobson, GA and Small, DH, Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells, Australian Neuroscience Society Annual Meeting, 29 January - 1 February, 2012, Gold Coast, Australia (2012) [Conference Extract]
Cui, H and Hung, AC and Freeman, C and Narkowicz, CK and Jacobson, GA and Small, DH, Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells, APSN 2012, 29 September - 2 October, 2012, Kobe, Japan (2012) [Conference Extract]
Small, DH and Klaver, D and Liu, S and Cui, H and Hoang, T and Hill, a and Wilce, MC and Aguilar, MI and Gasperini, RJ and Foa, LC, Disruption of protein trafficking in Alzheimer's Disease: APP, Aβ and AMPA receptors, Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] 
Cui, H and Hung, AC and Klaver, D and Narkowicz, CK and Jacobson, GA and Small, DH, Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice, Australian Neuroscience Society 31st Annual Meeting, 31 January - 3 February, 2011, Auckland, New Zealand (2011) [Conference Extract]
Hoang, T and Gasperini, RJ and Cui, H and Shepherd, CE and Strickland, DK and Foa, LC and Small, DH, Interaction of the receptor-associated protein (RAP) with APP and Aβ, Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] 
Landowski, LM and Gasperini, RJ and Small, DH and Taylor, BVM and West, AK and Foa, LC, Metallothionein I/II and metallothionein III induce growth cone chemotaxis via disparate mechanisms, Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] 
Hadrill, CE and Gasperini, RJ and Dickson, TC and Foa, LC and Small, DH, Regulation of the cell adhesion molecule, L1CAM by the Aβ peptide of Alzheimer's Disease, Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] 
Mitchell, C and Gasperini, RJ and Small, DH and Foa, LC, STIM1 is necessary for regulation of growth cone motility, Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] 
Entry
Southam, K and Stennard, FA and Small, DH, App, Encyclopedia of Signaling Molecules, S Choi (ed), pp. 1-8 (2016) [Entry]

This list was generated on Mon May 21 03:52:29 2018.