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Review of the prevalence of diabetic retinopathy in Indigenous Australians
journal contribution
posted on 2023-05-18, 08:29 authored by Kaidonis, G, Mills, RA, Landers, J, Franzco, SRL, Kathryn BurdonKathryn Burdon, Craig, JEThe purpose of this review is to compare the prevalence of diabetic retinopathy (DR) between Indigenous and non-Indigenous Australians with Diabetes Mellitus (DM). Australian DR prevalence data from 6 Indigenous studies (n = 2865) and 5 non-Indigenous studies (n = 9801) conducted between 1985 and 2013 were included for analysis. Estimated prevalence of any DR among Indigenous Australians with DM was 23.4% compared with 28.9% for non-Indigenous Australians (χ2 = 26.9, P < 0.001). In studies performed after 1990, a significantly higher rate of diabetic macular edema was found in Indigenous compared with nonIndigenous Australians with DM (7.6% versus 4.9%, χ2 = 6.67, P = 0.01). Although there are limitations in comparing these studies, one explanation for the observed data could be a model in which Indigenous Australians are relatively resistant to early stage DR, but with a subset progressing to sight threatening DR due to individual genetic and environmental susceptibility factors coupled with poor glycemic control.
History
Publication title
Clinical and Experimental OphthalmologyVolume
42Pagination
875-882ISSN
1442-6404Department/School
Menzies Institute for Medical ResearchPublisher
Blackwell Publishing AsiaPlace of publication
54 University St, P O Box 378, Carlton, Australia, Victoria, 3053Rights statement
Copyright 2014 Royal Australian and New Zealand College of OphthalmologistsRepository Status
- Restricted