eCite Digital Repository
Administration of surfactant using less invasive techniques as a part of a non-aggressive paradigm towards preterm infants
Citation
Aguar, M and Nunez, A and Cubells, E and Cernada, M and Dargaville, PA and Vento, M, Administration of surfactant using less invasive techniques as a part of a non-aggressive paradigm towards preterm infants, Early Human Development, 90, (Supplement 2) pp. S57-S59. ISSN 0378-3782 (2014) [Refereed Article]
Copyright Statement
Copyright 2014 Elsevier Ireland Ltd.
DOI: doi:10.1016/S0378-3782(14)50015-1
Abstract
Traditional treatment of respiratory distress syndrome in preterm infants consisted of early intubation, mechanical ventilation and intra-tracheal administration of exogenous surfactant. Recently, non-invasive ventilation, which has shown some advantages in short- and long-term outcomes, has gained popularity for the initial management of respiratory insufficiency in preterm infants. However, non-invasive ventilation from the outset poses difficulties in relation to administration of exogenous surfactant. The customary INSURE technique requires tracheal intubation, surfactant administration, and rapid extubation, but the latter is not always possible. As a more elegant approach, several minimally invasive techniques of delivering surfactant have been developed for babies spontaneously breathing on CPAP. The most extensively studied have been those in which the trachea is briefly catheterized with a nasogastric tube or vascular catheter, and exogenous surfactant is administered. Although results seem promising they are not yet conclusive, and further studies will be needed to answer a number of outstanding questions.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | Infant, preterm, Respiratory distress, Non-invasive ventilation, Pulmonary surfactants, Gentle approach |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Paediatrics |
Research Field: | Paediatrics not elsewhere classified |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Dargaville, PA (Professor Peter Dargaville) |
ID Code: | 99056 |
Year Published: | 2014 |
Web of Science® Times Cited: | 9 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2015-03-12 |
Last Modified: | 2017-11-06 |
Downloads: | 0 |
Repository Staff Only: item control page