File(s) under permanent embargo
Synthesis of nitrogen-substituted methylenecyclopropanes by strain-driven overman rearrangement of cyclopropenylmethyl trichloroacetimidates
journal contribution
posted on 2023-05-18, 08:16 authored by Howard, J, Amin, C, Lainhart, B, Jason SmithJason Smith, Rimington, J, Hyland, CJTNitrogen-substituted methylenecyclopropanes have been prepared by a strain-driven Overman rearrangement of cyclopropenylmethyl trichloroacetimidates. The reaction proceeds at room temperature and without the need of a transition-metal catalyst. Furthermore, it has been shown that C-3-substituted cyclopropenylmethyl trichloroacetimidates undergo a hydrolytic ring-opening reaction to form allenylcarbinols.
History
Publication title
The Journal of Organic ChemistryVolume
79Issue
17Pagination
8462-8468ISSN
0022-3263Department/School
School of Natural SciencesPublisher
Amer Chemical SocPlace of publication
1155 16th St, NW, Washington, USA, DC, 20036Rights statement
Copyright 2014 American Chemical SocietyRepository Status
- Restricted