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Intraocular pressure during femtosecond laser pretreatment: Comparison of glaucomatous eyes and nonglaucomatous eyes


Darian-Smith, E and Howie, A and Abell, RG and Kerr, N and Allen, PL and Vote, BJ and Toh, T, Intraocular pressure during femtosecond laser pretreatment: Comparison of glaucomatous eyes and nonglaucomatous eyes, Journal of Cataract and Refractive Surgery, 41, (2) pp. 272-277. ISSN 0886-3350 (2015) [Refereed Article]

Copyright Statement

Copyright 2015 ASCRS and ESCRS

DOI: doi:10.1016/j.jcrs.2014.10.026


Purpose: To compare changes in intraocular pressure (lOP) during femtosecond laser pretreatment of cataract between glaucomatous eyes and nonglaucomatous eyes.

Setting: Launceston Eye Institute and Launceston Eye Hospital, Launceston, Australia.

Design: Nonrandomized interventional prospective case series.

Methods: Patients with clinically stable primary open-angle glaucoma (POAG) having femtosecond laser pretreatment were compared with a concurrent cohort of patients with healthy eyes having the same procedure. Pretreatment was performed using a fluid-filled optical docking system (Liquid Optics Interface). With the patient supine, the lOP was measured at 4 time points using a rebound tonometer (lcare Pro).

Results: The study comprised 143 eyes of 97 patients. Forty-three eyes (30.1%) had documented glaucoma. The mean baseline lOP was 20.2 mm Hg 4.2 (SO) in glaucomatous eyes and 18.9 4.0 mm Hg in nonglaucomatous eyes (P=.06). The mean change in lOP values between each time frame and baseline was as follows: vacuum-on, 13.8 9.9 mm Hg and 11.1 6.9 mm Hg, respectively (P=.06); after treatment, 17.4 7.4 mm Hg and 14.1 7.2 mm Hg, respectively (P=.014); after undocking of vacuum, 9.9 5.4 mm Hg and 8.7 5.7 mm Hg, respectively (P=.24).

Conclusions: Femtosecond pretreatment caused a greater transient rise in lOP after treatment and a higher residual lOP after vacuum undocking in glaucomatous eyes than in nonglaucomatous eyes. This is well tolerated short term; however, long-term implications for eyes with glaucoma are unknown at present.

Item Details

Item Type:Refereed Article
Keywords:intraocular pressure, femtosecond laser, glaucomatous eyes
Research Division:Biomedical and Clinical Sciences
Research Group:Ophthalmology and optometry
Research Field:Ophthalmology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Treatment of human diseases and conditions
UTAS Author:Darian-Smith, E (Dr Erica Darian-Smith)
UTAS Author:Howie, A (Mr Allister Howie)
UTAS Author:Allen, PL (Dr Penny Allen)
UTAS Author:Vote, BJ (Dr Brendan Vote)
ID Code:98720
Year Published:2015
Web of Science® Times Cited:13
Deposited By:Medicine
Deposited On:2015-02-26
Last Modified:2017-11-07

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