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Capillary electrophoresis of natural products: 2011-2012

Citation

Tubaon, RMS and Rabanes, H and Haddad, PR and Quirino, JP, Capillary electrophoresis of natural products: 2011-2012, Electrophoresis, 35, (1) pp. 190-204. ISSN 0173-0835 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Wiley-VCH Verlag

DOI: doi:10.1002/elps.201300473

Abstract

Bioactive natural products are major sources of lead compounds for drug discovery and pharmaceutical development, therefore, innovative and current separation and characterization techniques are important for these compounds. Here, CE methods applied for the analysis of natural products published during 2011-2012 are reviewed. This is an updated version of an earlier review paper in this journal, which highlighted developments during 2006-2010. The major method developments over the review period centered on derivatization, chiral analysis, modes of detection, stacking or on-line sample concentration, and sample preparation (predominantly using extraction methods). The samples analyzed were herbal products, foods, soil, and biological samples. Developments also occurred in the areas of quality control, toxicology assessment, and enzyme-inhibitor screening. A table that summarizes the areas, source of natural product, nature of the bioactive analyte, CE conditions, LODs, and corresponding reference is provided. A short description on the theory of CE and insights on future activities of CE on natural products are also presented.

Item Details

Item Type:Refereed Article
Keywords:CE, CZE, MEKC, natural products
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Tubaon, RMS (Ms Ria Tubaon)
Author:Rabanes, H (Ms Heide Rabanes)
Author:Haddad, PR (Professor Paul Haddad)
Author:Quirino, JP (Associate Professor Lito Quirino)
ID Code:98479
Year Published:2014
Web of Science® Times Cited:13
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2015-02-17
Last Modified:2017-10-27
Downloads:0

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