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Novel oral anticoagulants in atrial fibrillation


Bereznicki, L, Novel oral anticoagulants in atrial fibrillation, Australian Pharmacist, 33, (10) pp. 62-66. ISSN 0728-4632 (2014) [Professional, Refereed Article]

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Copyright 2014 Pharmaceutical Society of Australia Ltd.

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You are reviewing the medication profile of Mrs HH, a 76-year-old woman with a history of atrial fibrillation and hypertension. Her renal and hepatic function are normal. She is currently taking enalapril 20 mg/ hydrochlorothiazide 6 mg once daily, metoprolol 50 mg twice daily and aspirin 100 mg once daily. You notice she has risk factors for stroke (age and hypertension), no apparent risk factors for bleeding apart from her age and use of aspirin (hypertension is we/I-controlled), so you decide to recommend her GP consider prescribing an anticoagulant. You are aware that, in addition to warfarin, several new anticoagulant medicines are available. Which anticoagulant would you recommend?

After reading this article, pharmacists should be able to:

  • Describe the mechanism of action of novel anticoagulants (NOACs)
  • Outline and compare the characteristics of NOACs
  • Discuss how NOACs differ with respect to effectiveness, precautions, contraindications and adverse effect profies.

Item Details

Item Type:Professional, Refereed Article
Keywords:anticoagulant, atrial fibrillation
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Pharmaceutical sciences
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Bereznicki, L (Professor Luke Bereznicki)
ID Code:97219
Year Published:2014
Deposited By:Pharmacy
Deposited On:2014-12-08
Last Modified:2015-06-09

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