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Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults

Citation

Scott, D and Ebeling, PR and Sanders, KM and Aitken, D and Winzenberg, T and Jones, G, Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults, Journal of Clinical Endocrinology and Metabolism, 100, (2) pp. 670-678. ISSN 1945-7197 (2015) [Refereed Article]

Copyright Statement

Copyright 2015 by the Endocrine Society

DOI: doi:10.1210/jc.2014-3519

Abstract

Context: High vitamin D and physical activity (PA) levels are independently associated with improved body composition and muscle function in older adults.

Objective: To investigate the interaction of 25-hydroxyvitamin D (25OHD) and PA status in maintenance of body composition and muscle function in older adults.

Design and Setting: A five-year prospective population-based study of Australian community-dwelling older adults.

Participants: 615 community-dwelling volunteers aged ≥ 50 years (61.4 6.9 [mean SD] years; 48% female) randomly selected from electoral rolls and categorised according to baseline serum 25OHD (≥ or < 50nmol/L) and PA (≥ or < 10,000 pedometer-determined steps/day) levels as: high 25OHD and high PA (VitD+PA+); high 25OHD and low PA (VitD+PA-); low 25OHD and high PA (VitD-PA+); low 25OHD and low PA (VitD-PA-). A subset of 518 participants completed accelerometer assessments during follow-up.

Main Outcome Measures: Changes in DXA-assessed body composition and lower-limb muscle function.

Results: VitD+PA+ had significantly smaller increases in body fat over five years compared to other groups (all PP<0.05). Higher baseline pedometer-determined PA resulted in declines in total body fat (β=-0.23kg per 100 steps/day, P=0.001) over five years for participants with high 25OHD, but not those with low 25OHD (P>0.05). Amongst participants with accelerometer data, these associations were generally mediated by higher levels of moderate/vigorous PA.

Conclusions: High vitamin D status appears to enhance PA-related declines in body fat during ageing but the mechanism may be greater amounts of outdoor moderate/vigorous PA rather than a direct effect of 25OHD.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Rheumatology and Arthritis
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Skeletal System and Disorders (incl. Arthritis)
Author:Aitken, D (Dr Dawn Aitken)
Author:Winzenberg, T (Professor Tania Winzenberg)
Author:Jones, G (Professor Graeme Jones)
ID Code:97083
Year Published:2015 (online first 2014)
Web of Science® Times Cited:9
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-12-02
Last Modified:2017-11-03
Downloads:0

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