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A transdermal patch of trouble
A 79-year-old man, with a history of penicillin allergy, hypertension, diabetes mellitus, and multiple vertebral fractures secondary to severe osteoporosis, developed a pruritic, erythematous reaction limited to the site of application of transdermal buprenorphine.
He had been applying transdermal buprenorphine patches for several weeks for chronic back pain before the lesions developed. After withdrawal of the transdermal buprenorphine and the use of topical high-potency corticosteroids, the lesions resolved. Skin patch tests with transdermal buprenorphine showed a papular erythematous reaction, suggesting a delayed hypersensitivity reaction.
History
Publication title
Australian PharmacistVolume
33Issue
9Pagination
33-34ISSN
0728-4632Department/School
School of Pharmacy and PharmacologyPublisher
Pharmaceutical Society of AustraliaPlace of publication
Deakin West, ACT.Rights statement
Copyright 2014 Pharmaceutical Society of AustraliaRepository Status
- Restricted