Nuotio, J and Oikonen, M and Magnussen, CG and Jokinen, E and Laitinen, T and Hutri-Kahonen, N and Kahonen, M and Lehtimaki, T and Taittonen, L and Tossavainen, P and Jula, A and Loo, B-M and Viikari, JS and Raitakari, OT and Juonala, M, Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study, Scandinavian Journal of Public Health, 42, (7) pp. 563-571. ISSN 1403-4948 (2014) [Refereed Article]
Copyright 2014 Sage Publications
Methods: The study population comprised 2063 Finnish adults aged 34-49 years (45% male). Lipid and blood pressure levels, glucose and anthropometry were measured and life style risk factors examined with questionnaires.
Results: Mean total cholesterol level in 2011 was 5.19 mmol/l, low density lipoprotein (LDL)-cholesterol 3.27 mmol/l, high density lipoprotein (HDL)-cholesterol 1.33 mmol/l, and triglycerides 1.34 mmol/l. Using American Diabetes Association criteria, Type 2 diabetes (T2D) was observed in 4.1% and prediabetes (fasting glucose 5.6-6.9 mmol/l or glycated hemoglobin 5.7-6.4%) diagnosed for 33.8% of the participants. Significant changes (P < 0.05) between 2007 and 2011 included an increase in waist circumference (3.3%) in women. In both sexes, systolic (-3.0% in women, -4.0% in men) and diastolic (-3.0% in women, -3.3% in men) blood pressure and triglycerides (-3.4% in women, -6.5% in men) decreased during follow-up.
Conclusions: Previously observed favorable trends in LDL-cholesterol levels have leveled off among a sample of young and middle-aged adults in Finland. Triglyceride and blood pressure levels have decreased. Over one-third of the study population had prediabetes and may be at increased risk for T2D.
|Item Type:||Refereed Article|
|Keywords:||Cardiovascular, risk factors, secular trend|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|Author:||Magnussen, CG (Dr Costan Magnussen)|
|Web of Science® Times Cited:||16|
|Deposited By:||Menzies Institute for Medical Research|
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