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Comparison of monochromatic aberrations in young adults with different visual acuity and refractive errors


Yazar, S and Hewitt, AW and Forward, H and McKnight, CM and Tan, A and Mountain, JA and Mackey, DA, Comparison of monochromatic aberrations in young adults with different visual acuity and refractive errors, Journal of Cataract and Refractive Surgery, 40, (3) pp. 441-449. ISSN 0886-3350 (2014) [Refereed Article]

DOI: doi:10.1016/j.jcrs.2013.07.055


PURPOSE: To compare the monochromatic aberrations in a large cohort of 20-year-old Australians with differing levels of visual acuity and explore the relationship between these aberrations and refractive error.

SETTING: Lions Eye Institute, Perth, Western Australia, Australia.

DESIGN: Cross-sectional analysis of a population-based cohort.

METHODS: Monochromatic aberrations were measured using a Zywave II wavefront aberrometer with natural pupils in a dark room. The logMAR corrected distance visual acuity (CDVA) was measured monocularly under normal illumination. Cycloplegic autorefraction was also performed.

RESULTS: The study enrolled 2039 eyes of 1040 participants. Data from 1007 right eyes were analyzed. The median CDVA and spherical equivalent were -0.06 logMAR (interquartile range [IQR], -0.10 to 0.00) and +0.25 diopters (D) (IQR, -0.38 to 0.63), respectively. The median 6.0 mm higher-order aberration (HOA) was 0.58 μm (IQR, 0.44 to 0.79). Coma-like aberrations and 3rd-, 4th-, and 5th-order HOAs were significantly different between subjects with a CDVA of -0.10 logMAR or better and those with a CDVA worse than -0.10 logMAR. Fourth-order aberrations Z(4,-4) (P=.024) and Z(4,-2) (P=.029) and 2nd-order aberration Z(2,0) (P<.001) differed significantly between myopic eyes, emmetropic eyes, and hyperopic eyes. Subjects with higher myopia had slightly higher total HOAs.

CONCLUSIONS: The HOAs in this population were marginally higher than previously reported values. The findings confirm there is a difference in monochromatic aberrations between different vision and refractive groups. Results in this study will benefit decision-making processes in the clinical setting.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Ophthalmology and optometry
Research Field:Ophthalmology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Hewitt, AW (Professor Alex Hewitt)
UTAS Author:Mackey, DA (Professor David Mackey)
ID Code:96455
Year Published:2014
Web of Science® Times Cited:11
Deposited By:Medicine
Deposited On:2014-11-06
Last Modified:2017-11-07

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