Meszaros, D and Burgess, J and Walters, EH and Johns, D and Markos, J and Giles, G and Hopper, J and Abramson, M and Dharmage, SC and Matheson, M, Domestic airborne pollutants and asthma and respiratory symptoms in middle age, Respirology, 19, (3) pp. 411-418. ISSN 1323-7799 (2014) [Refereed Article]
Copyright 2014 The Authors
Background and objective: The role of indoor air pollution as a risk factor for asthma and respiratory symptoms in middle age is unclear. We investigated associations between indoor air pollution sources and (i) asthma phenotypes and (ii) asthma-related respiratory symptoms in middle-aged adults.
Methods: Subjects (n = 5729) who participated in the 2004 survey of the Tasmanian Longitudinal Health Study completed respiratory and home environment questionnaires. Associations between indoor air pollution sources, and asthma phenotypes and asthma-related respiratory symptoms were estimated.
Results: Recent mould in the home was associated with current asthma (odds ratio (OR) 1.26; 95% confidence interval 1.06–1.50), wheeze (OR 1.34; 1.17–1.54) and nocturnal chest tightness (OR 1.30; 1.12–1.51). Stratified by atopy and gender, recent mould was associated with current non-atopic asthma only in males (OR 3.73; 1.29–10.80). More rooms affected by mould were associated with significant trends for current asthma, wheeze and nocturnal chest tightness. Home environmental tobacco smoke was associated with doctor-diagnosed asthma (OR 1.25; 1.02–1.53), wheeze (OR 1.69; 1.41–2.03), nocturnal chest tightness (OR 1.54; 1.26–1.88), with current asthma only in non-smokers (OR 2.09; 95%: 1.30–3.35) and with current asthma only in males (OR 1.74; 95%: 1.25–2.42). Among heating appliances, reverse cycle air conditioning was negatively associated with doctor-diagnosed asthma (OR 0.84; 0.70–1.00). Neither electric nor gas stove use was associated with either asthma phenotype or with asthma-related respiratory symptoms.
Conclusions: In middle age, reducing home exposure to mould and environmental tobacco smoke might reduce asthma and asthma-related respiratory symptoms.
|Item Type:||Refereed Article|
|Keywords:||asthma, cohort study, environmental tobacco smoke, mould, risk factor|
|Research Division:||Medical and Health Sciences|
|Research Group:||Cardiorespiratory Medicine and Haematology|
|Research Field:||Respiratory Diseases|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Respiratory System and Diseases (incl. Asthma)|
|Author:||Meszaros, D (Dr Desiree Meszaros)|
|Author:||Walters, EH (Professor Haydn Walters)|
|Author:||Johns, D (Associate Professor David Johns)|
|Web of Science® Times Cited:||5|
|Deposited By:||Medicine (Discipline)|
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