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Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum

journal contribution
posted on 2023-05-18, 04:22 authored by Ormonde, P, Horstedt, P, O'Toole, R, Milton, DL
To understand further the role of the flagellum of Vibrio anguillarum in virulence, invasive and adhesive properties of isogenic motility mutants were analyzed by using a chinook salmon embryo cell line. Adhesion was unaffected but invasion of the cell line was significantly decreased in nonmotile or partially motile mutants, and the chemotactic mutant was hyperinvasive. These results suggest that active motility aids invasion by V. anguillarum, both in vivo and in vitro.

History

Publication title

Journal of Bacteriology

Volume

182

Issue

8

Pagination

2326-2328

ISSN

0021-9193

Department/School

Tasmanian School of Medicine

Publisher

Amer Soc Microbiology

Place of publication

1752 N St Nw, Washington, USA, Dc, 20036-2904

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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