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Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum

Citation

Ormonde, P and Horstedt, P and O'Toole, R and Milton, DL, Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum, Journal of Bacteriology, 182, (8) pp. 2326-2328. ISSN 0021-9193 (2000) [Refereed Article]

DOI: doi:10.1128/JB.182.8.2326-2328.2000

Abstract

To understand further the role of the flagellum of Vibrio anguillarum in virulence, invasive and adhesive properties of isogenic motility mutants were analyzed by using a chinook salmon embryo cell line. Adhesion was unaffected but invasion of the cell line was significantly decreased in nonmotile or partially motile mutants, and the chemotactic mutant was hyperinvasive. These results suggest that active motility aids invasion by V. anguillarum, both in vivo and in vitro.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Microbiology
Research Field:Bacteriology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Infectious Diseases
Author:O'Toole, R (Dr Ronan O'Toole)
ID Code:95798
Year Published:2000
Web of Science® Times Cited:59
Deposited By:Medicine (Discipline)
Deposited On:2014-10-08
Last Modified:2014-10-08
Downloads:0

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