File(s) not publicly available
Effect of Hyperglycemia on Cardiac Autonomic Function in Type 2 Diabetes
conference contribution
posted on 2023-05-23, 09:26 authored by Tarvainen, MP, Lipponen, JA, Al-Aubaidy, H, Jelinek, HFHeart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation which has been associated with increased risk for cardiac events. In this paper, we examined the associations of blood glucose level (BGL) and duration of diabetes with autonomic nervous system (ANS) function assessed by HRV analysis. Resting HRV and BGL measures of 32 healthy controls and 54 type 2 DM (T2DM) patients were analyzed. HRV data were analyzed using time-domain, frequency-domain and nonlinear methods. HRV parameters showed a clear difference between controls and T2DM patients. BGL correlated negatively with mean RR interval. In addition, a decrease in HRV was observed in hyperglycemia, most clear changes shown in triangular interpolation of RR interval histogram (TINN), root mean square of successive RR interval differences (RMSSD) and Poincar´e plot index SD1. Duration of diabetes was clearly associated with decreased HRV, shown by decreases in standard deviation of RR intervals (SDNN), HRV triangular index (HRVi), TINN, LF power and Poincar´e plot index SD2. Glycemic values were not associated with disease duration.
History
Publication title
Computing in CardiologyVolume
39Pagination
405-408ISSN
0276-6574Department/School
Tasmanian School of MedicinePublisher
I E E E Computer SocietyPlace of publication
United StatesEvent title
2012 Computing in Cardiology ConferenceEvent Venue
Krakow, PolandDate of Event (Start Date)
2012-09-09Date of Event (End Date)
2012-09-12Repository Status
- Restricted