Bereznicki, BJ and Peterson, GM and Jackson, SL and Walters, E and Hardley, FL and Gavagna, GA and Marshall, DC, Describing drivers of and barriers to persistence with tiotropium in patients with chronic obstructive pulmonary disease: A mixed-methods approach, International Journal of Pharmacy Practice, 32, (2) pp. 154-157. ISSN 0961-7671 (2015) [Refereed Article]
Copyright 2014 Royal Pharmaceutical Society
Objective: To understand the factors influencing persistence with tiotropium in patients with chronic obstructive pulmonary disease (COPD).
Methods: Patients classified as 'persistent' or 'non-persistent' with tiotropium were identified from pharmacy dispensing records. Patients were compared for health status, beliefs and behaviours using data from questionnaires and interviews.
Key findings: Perceptions of the risks and benefits of medication, fear of worsening illness, and the GP's emphasis on the importance of the medication were key determinants of tiotropium persistence.
Conclusions: Perceptions, attitudes and beliefs of patients and doctors influence persistence with tiotropium. These complex interactions need to be targeted to improve persistence with medicines in COPD.
|Item Type:||Refereed Article|
|Keywords:||chronic obstructive pulmonary disease, community pharmacy, data-mining, medication persistence|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Research Field:||Public Health and Health Services not elsewhere classified|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Preventive Medicine|
|Author:||Bereznicki, BJ (Dr Bonnie Bereznicki)|
|Author:||Peterson, GM (Professor Gregory Peterson)|
|Author:||Jackson, SL (Dr Shane Jackson)|
|Author:||Walters, E (Professor Haydn Walters)|
|Year Published:||2015 (online first 2014)|
|Web of Science® Times Cited:||1|
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