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Modeling cognitive reserve in healthy middle-aged and older adults: the Tasmanian Healthy Brain Project


Ward, DD and Summers, MJ and Saunders, NL and Vickers, JC, Modeling cognitive reserve in healthy middle-aged and older adults: the Tasmanian Healthy Brain Project, International Psychogeriatrics, 27, (4) pp. 579-589. ISSN 1041-6102 (2015) [Refereed Article]

Copyright Statement

Copyright 2014 Springer Publishing Co

DOI: doi:10.1017/S1041610214002075


Background: Cognitive reserve (CR) is a protective factor that supports cognition by increasing the resilience of an individual’s cognitive function to the deleterious effects of cerebral lesions. A single environmental proxy indicator is often used to estimate CR (e.g. education), possibly resulting in a loss of the accuracy and predictive power of the investigation. Furthermore, while estimates of an individual’s prior CR can be made, no operational measure exists to estimate dynamic change in CR resulting from exposure to new life experiences.

Methods: We aimed to develop two latent measures of CR through factor analysis: prior and current, in a sample of 467 healthy older adults.

Results: The prior CR measure combined proxy measures traditionally associated with CR, while the current CR measure combined variables that had the potential to reflect dynamic change in CR due to new life experiences. Our main finding was that the analyses uncovered latent variables in hypothesized prior and current models of CR.

Conclusions: The prior CR model supports multivariate estimation of pre-existing CR and may be applied to more accurately estimate CR in the absence of neuropathological data. The current CR model may be applied to evaluate and explore the potential benefits of CR-based interventions prior to dementia onset.

Item Details

Item Type:Refereed Article
Keywords:cognitive reserve, aging, cognition, measurement, education, intelligence, lifestyle
Research Division:Psychology
Research Group:Biological psychology
Research Field:Behavioural neuroscience
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Ward, DD (Mr David Ward)
UTAS Author:Summers, MJ (Dr Mathew Summers)
UTAS Author:Saunders, NL (Dr Nichole Saunders)
UTAS Author:Vickers, JC (Professor James Vickers)
ID Code:95108
Year Published:2015 (online first 2014)
Funding Support:National Health and Medical Research Council (1003645)
Web of Science® Times Cited:16
Deposited By:Psychology
Deposited On:2014-09-24
Last Modified:2017-11-06

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