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Long-term efficacy of a tele-health intervention for acute coronary syndrome patients with depression: 12-month results of the MoodCare randomized controlled trial

Citation

O'Neil, A and Taylor, B and Hare, DL and Sanderson, K and Cyril, S and Venugopal, K and Chan, B and Atherton, JJ and Hawkes, A and Walters, DL and Oldenburg, B, and on behalf of the MoodCare Investigator Team, Long-term efficacy of a tele-health intervention for acute coronary syndrome patients with depression: 12-month results of the MoodCare randomized controlled trial, European Journal of Preventive Cardiology pp. 1-10. ISSN 2047-4881 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Sage Publications

DOI: doi:10.1177/2047487314547655

Abstract

BACKGROUND: Depression is common after a cardiac event; however it often remains untreated. Previously, we reported the efficacy and feasibility of a 6-month tele-health programme (MoodCare), which integrates depression management into a cardiovascular disease (CVD) risk reduction programme for Acute Coronary Syndrome (ACS) patients with low mood. Here, we evaluate the long-term efficacy of the programme at 12-month follow-up.

DESIGN: A two-arm, parallel, randomized design to compare the long-term effects of 'MoodCare' (n = 61) to usual care (UC) (n = 60) at 12 months.

METHOD: 121 ACS patients recruited from six hospitals in Victoria and Brisbane, Australia were randomized to a telephone-delivered cognitive behavioural therapy and risk-reduction programme or usual medical care. Mixed-model repeated measurements (MMRM) analysis was applied with results expressed as estimated marginal mean changes in depression and health-related quality of life (HRQOL) outcomes by group.

RESULTS: After 12 months, treatment effects were observed for those with major depressive disorder (MDD) for PHQ-9 depression (MoodCare: mean score: 6.5; 95% CI: 4.9-8.0 versus UC: 9.3; 95% CI: 7.7-10.9, p = 0.012)) and SF-12 mental health scores (MoodCare: 42.5; 95% CI: 39.8-45.2 versus UC: 36.8; 95% CI: 34.1-39.6, p = 0.005). No beneficial treatment effects were observed in those with no MDD at baseline.

CONCLUSION: After 12 months, MoodCare was superior to UC for improving mental health outcomes for those with a clinical diagnosis of major depression. Our findings support the implementation of depression-based interventions for cardiac patients with a clinical diagnosis of depression and provide evidence of longer term efficacy to one year.

Item Details

Item Type:Refereed Article
Keywords:Depression; acute coronary syndrome; cardiac; cognitive behaviour therapy; tele-health
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Psychiatry (incl. Psychotherapy)
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Mental Health
Author:Sanderson, K (Associate Professor Kristy Sanderson)
ID Code:94742
Year Published:2014
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-09-16
Last Modified:2015-02-11
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