O'Neil, A and Taylor, B and Hare, DL and Sanderson, K and Cyril, S and Venugopal, K and Chan, B and Atherton, JJ and Hawkes, A and Walters, DL and Oldenburg, B, and on behalf of the MoodCare Investigator Team, Long-term efficacy of a tele-health intervention for acute coronary syndrome patients with depression: 12-month results of the MoodCare randomized controlled trial, European Journal of Preventive Cardiology pp. 1-10. ISSN 2047-4881 (2014) [Refereed Article]
Copyright 2014 Sage Publications
DESIGN: A two-arm, parallel, randomized design to compare the long-term effects of 'MoodCare' (n = 61) to usual care (UC) (n = 60) at 12 months.
METHOD: 121 ACS patients recruited from six hospitals in Victoria and Brisbane, Australia were randomized to a telephone-delivered cognitive behavioural therapy and risk-reduction programme or usual medical care. Mixed-model repeated measurements (MMRM) analysis was applied with results expressed as estimated marginal mean changes in depression and health-related quality of life (HRQOL) outcomes by group.
RESULTS: After 12 months, treatment effects were observed for those with major depressive disorder (MDD) for PHQ-9 depression (MoodCare: mean score: 6.5; 95% CI: 4.9-8.0 versus UC: 9.3; 95% CI: 7.7-10.9, p = 0.012)) and SF-12 mental health scores (MoodCare: 42.5; 95% CI: 39.8-45.2 versus UC: 36.8; 95% CI: 34.1-39.6, p = 0.005). No beneficial treatment effects were observed in those with no MDD at baseline.
CONCLUSION: After 12 months, MoodCare was superior to UC for improving mental health outcomes for those with a clinical diagnosis of major depression. Our findings support the implementation of depression-based interventions for cardiac patients with a clinical diagnosis of depression and provide evidence of longer term efficacy to one year.
|Item Type:||Refereed Article|
|Keywords:||Depression; acute coronary syndrome; cardiac; cognitive behaviour therapy; tele-health|
|Research Division:||Medical and Health Sciences|
|Research Group:||Clinical Sciences|
|Research Field:||Psychiatry (incl. Psychotherapy)|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Mental Health|
|Author:||Sanderson, K (Associate Professor Kristy Sanderson)|
|Deposited By:||Menzies Institute for Medical Research|
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