eCite Digital Repository

Impact of the pharmacist medication review services on drug-related problems and potentially inappropriate prescribing of renally cleared medications in residents of aged care facilities

Citation

Gheewala, PA and Peterson, GM and Curtain, CM and Nishtala, PS and Hannan, PJ and Castelino, RL, Impact of the pharmacist medication review services on drug-related problems and potentially inappropriate prescribing of renally cleared medications in residents of aged care facilities, Drugs and Aging, 31, (11) pp. 825-835. ISSN 1170-229X (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Springer International Publishing Switzerland

DOI: doi:10.1007/s40266-014-0208-y

Abstract

Background: Drug-related problems (DRPs) are common in aged care facilities and few studies have been conducted to determine the impact of the pharmacist-conducted medication review services. Studies determining the prevalence of chronic kidney disease (CKD) and data regarding inappropriate prescribing of renally cleared medications in aged care facilities in Australia are also lacking.

Objectives: To investigate the number and nature of DRPs identified and recommendations made by pharmacists in residents of aged care facilities. To determine the prevalence of CKD and estimate the magnitude of inappropriate prescribing of renally cleared medications in residents of aged care facilities.

Methods: DRPs identified and recommendations made by pharmacists were classified using the adapted version of the DOCUMENT classification system. The modification of diet in renal disease formula was used to estimate the prevalence of CKD, and the Cockcroft-Gault formula was used to estimate the magnitude of inappropriate prescribing of renally cleared medications.

Results: Over 98 % of residents of aged care facilities had at least one DRP. Most (83.8 %) recommendations made by accredited pharmacists to resolve DRPs were accepted by general practitioners. CKD was prevalent in 48 % of residents, and inappropriate prescribing of renally cleared medications was identified in 28 (16 %) residents with CKD.

Conclusions: DRPs are common in aged care facilities and the impact of medication review services appears to be high. CKD is also common among residents of aged care facilities, and inappropriate prescribing of renally cleared medications was also prevalent, warranting attention to regular renal function monitoring and appropriate drug and dose selection in residents of aged care facilities.

Item Details

Item Type:Refereed Article
Keywords:medication reviews, renally cleared medications, inappropriate prescribing, aged-care
Research Division:Medical and Health Sciences
Research Group:Pharmacology and Pharmaceutical Sciences
Research Field:Pharmaceutical Sciences
Objective Division:Health
Objective Group:Other Health
Objective Field:Health not elsewhere classified
Author:Gheewala, PA (Miss Pankti Gheewala)
Author:Peterson, GM (Professor Gregory Peterson)
Author:Curtain, CM (Mr Colin Curtain)
Author:Castelino, RL (Dr Ronald Castelino)
ID Code:94511
Year Published:2014
Web of Science® Times Cited:12
Deposited By:Pharmacy
Deposited On:2014-09-10
Last Modified:2016-11-17
Downloads:0

Repository Staff Only: item control page