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Evaluation of a Brachial Cuff and Suprasystolic Waveform Algorithm Method to Noninvasively Derive Central Blood Pressure


Costello, BT and Schultz, MG and Black, JA and Sharman, JE, Evaluation of a Brachial Cuff and Suprasystolic Waveform Algorithm Method to Noninvasively Derive Central Blood Pressure, American Journal of Hypertension, 28, (4) pp. 480-486. ISSN 0895-7061 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 American Journal of Hypertension, Ltd

DOI: doi:10.1093/ajh/hpu163


BACKGROUND: Central blood pressure (BP) can be estimated noninvasively by analyzing brachial artery waveforms. In this study, our aim was to assess the validity of a brachial cuff-based (suprasystolic) technique for estimating central BP (CBPestimated) by comparison with invasive aortic BP (CBPinvasive). METHODS: Eighty-four simultaneous CBPestimated (Pulsecor R7.0) and CBPinvasive measures were recorded in 47 patients (aged 6310 years, 62% male) undergoing coronary angiography. Measures were captured at baseline and acutely following intravenous glyceryl trinitrate (GTN; 100-200 μg). Mean CBPinvasive systolic BP (SBP) and diastolic BP (DBP) were compared with CBPestimated SBP and DBP calibrated with brachial SBP and DBP recorded from the Pulsecor device. To test validity of the central BP algorithm, measures of CBPestimated SBP were also compared with CBPinvasive SBP following recalibration with invasive mean arterial pressure (MAP) and DBP. RESULTS: At baseline, mean difference standard deviation between CBPestimated SBP and CBPinvasive SBP was -79mm Hg (intraclass correlation coefficient (ICC) = 0.86; P < 0.001) with similar underestimation post-GTN (-69mm Hg; ICC = 0.90; P < 0.001). Recalibration of CBPestimated SBP with invasive MAP and DBP resulted in closer mean difference to CBPinvasive SBP (-27mm Hg; ICC = 0.95; P < 0.001) at baseline but not post-GTN (-67mm Hg; ICC = 0.95; P < 0.001). CONCLUSIONS: The Pulsecor algorithm to derive central BP has acceptable validity when calibrated with invasive pressures. However, accuracy is compromised when noninvasive brachial cuff BP calibration is used.

Item Details

Item Type:Refereed Article
Keywords:blood pressure; central blood pressure; hypertension; monitoring; oscillometric; suprasystolic; validation
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Schultz, MG (Dr Martin Schultz)
UTAS Author:Sharman, JE (Professor James Sharman)
ID Code:94417
Year Published:2014
Web of Science® Times Cited:22
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-09-09
Last Modified:2017-12-06

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