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Infant sleeping environment and asthma at 7 years: A prospective cohort study


Trevillian, LF and Ponsonby, AL and Dwyer, T and Kemp, A and Cochrane, J and Lim, LL-Y and Carmichael, A, Infant sleeping environment and asthma at 7 years: A prospective cohort study, American Journal of Public Health, 95, (12) pp. 2238-2245. ISSN 0090-0036 (2005) [Refereed Article]

DOI: doi:10.2105/AJPH.2004.047191


Objectives. We investigated the role of infant bedding items, as part of a composite bedding environment, in the development of childhood wheezing. Methods. This prospective cohort investigation involved 863 children who participated in an infant survey in 1988 and an asthma study in Tasmania, Australia, in 1995. The derived 3 composite infant bedding categories corresponded to increasing numbers of house dust mite (HDM)-rich bedding items used. Outcomes measured included recent and frequent wheezing. Results. Composite infant bedding used was associated with recent wheezing. Effects increased at increasing levels of HDM-rich bedding items used. Effects were further enhanced by home environmental factors of bedroom heating, recent bedroom painting, and absence of bedroom carpeting. When any 2 or more of these environmental factors were present, a strong dose-response relationship was evident. Conclusions. Our results show that bedding exposures in infancy are prospectively associated with childhood wheezing and that home environmental conditions may modify this association.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Ponsonby, AL (Professor Anne Ponsonby)
Author:Dwyer, T (Professor Terry Dwyer)
Author:Cochrane, J (Mrs Jennifer Cochrane)
Author:Carmichael, A (Professor Allan Carmichael)
ID Code:92685
Year Published:2005
Web of Science® Times Cited:13
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-06-25
Last Modified:2014-06-25

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