eCite Digital Repository

Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study


Tettey, P and Simpson Jr, S and Taylor, B and Blizzard, L and Ponsonby, A-L and Dwyer, T and Kostner, K and van der Mei, I, Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study, Journal of the Neurological Sciences, 340, (1-2) pp. 230-232. ISSN 1878-5883 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Elsevier

DOI: doi:10.1016/j.jns.2014.02.038


Background There is increasing evidence that serum lipids and apolipoproteins may be associated with multiple sclerosis (MS) clinical course. Objective To investigate the associations between serum lipids, apolipoproteins, body mass index and relapse in MS. Methods A prospective cohort of 141 participants with relapsing-remitting MS was followed from 2002 to 2005. Serum lipid and apolipoprotein levels were measured biannually, and body mass index at baseline. The association with hazard of relapse was assessed using survival analysis. Results Neither body mass index nor any of the lipid-related measures were associated with the hazard of relapse. Conclusion Serum lipid profile and body mass index are not associated with the hazard of relapse in MS. © 2014 Elsevier B.V. All rights reserved.

Item Details

Item Type:Refereed Article
Keywords:Lipid, Cholesterol, Apolipoprotein, Relapse, Multiple sclerosis, Pro!le
Research Division:Health Sciences
Research Group:Epidemiology
Research Field:Epidemiology not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Tettey, P (Mr Prudence Tettey)
UTAS Author:Simpson Jr, S (Dr Steve Simpson JR)
UTAS Author:Taylor, B (Professor Bruce Taylor)
UTAS Author:Blizzard, L (Professor Leigh Blizzard)
UTAS Author:van der Mei, I (Professor Ingrid van der Mei)
ID Code:92230
Year Published:2014
Web of Science® Times Cited:29
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-06-10
Last Modified:2017-11-07

Repository Staff Only: item control page