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Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study

Citation

Tettey, P and Simpson Jr, S and Taylor, B and Blizzard, L and Ponsonby, A-L and Dwyer, T and Kostner, K and van der Mei, I, Adverse lipid profile is not associated with relapse risk in MS: Results from an observational cohort study, Journal of the Neurological Sciences, 340, (1-2) pp. 230-232. ISSN 1878-5883 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Elsevier

DOI: doi:10.1016/j.jns.2014.02.038

Abstract

Background There is increasing evidence that serum lipids and apolipoproteins may be associated with multiple sclerosis (MS) clinical course. Objective To investigate the associations between serum lipids, apolipoproteins, body mass index and relapse in MS. Methods A prospective cohort of 141 participants with relapsing-remitting MS was followed from 2002 to 2005. Serum lipid and apolipoprotein levels were measured biannually, and body mass index at baseline. The association with hazard of relapse was assessed using survival analysis. Results Neither body mass index nor any of the lipid-related measures were associated with the hazard of relapse. Conclusion Serum lipid profile and body mass index are not associated with the hazard of relapse in MS. © 2014 Elsevier B.V. All rights reserved.

Item Details

Item Type:Refereed Article
Keywords:Lipid, Cholesterol, Apolipoprotein, Relapse, Multiple sclerosis, Pro!le
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Nervous System and Disorders
Author:Tettey, P (Mr Prudence Tettey)
Author:Simpson Jr, S (Dr Steve Simpson JR)
Author:Taylor, B (Professor Bruce Taylor)
Author:Blizzard, L (Professor Leigh Blizzard)
Author:van der Mei, I (Associate Professor Ingrid van der Mei)
ID Code:92230
Year Published:2014
Web of Science® Times Cited:16
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-06-10
Last Modified:2017-11-07
Downloads:0

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