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The Association Between Hip Muscle Cross-Sectional Area, Muscle Strength, and Bone Mineral Density

Citation

Ahedi, HK and Aitken, D and Scott, D and Blizzard, L and Cicuttini, F and Jones, G, The Association Between Hip Muscle Cross-Sectional Area, Muscle Strength, and Bone Mineral Density, Calcified Tissue International, 95, (1) pp. 64-72. ISSN 1432-0827 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Springer Science+Business Media

DOI: doi:10.1007/s00223-014-9863-6

Abstract

Studies examining the association between muscle size, muscle strength, and bone mineral density (BMD) are limited. Thus, this study aimed to describe the association between hip muscles cross-sectional area (CSA), muscle strength, and BMD of the hip and spine. A total of 321 subjects from the Tasmanian Older Adult Cohort study with a right hip MRI scan conducted between 2004 and 2006 were included. Hip muscles were measured on MR images by OsiriX (Geneva) software measuring maximum muscle CSA (cm2) of gluteus maximus, obturator externus, gemelli, quadratus femoris, piriformis, pectineus, sartorius, and iliopsoas. Dual-energy X-ray absorptiometry measured total hip, femoral neck, and spine BMD, and lower limb muscle strength was assessed by dynamometer. Muscle CSA of the hip flexors (pectineus, sartorius, and iliopsoas) and the hip rotators, obturator externus, and quadratus femoris were associated with both total hip and femoral neck BMD (all p < 0.05). The associations between CSA of pectineus and sartorius and BMD were stronger in women (p = 0.01-0.001) compared to men (p = 0.12-0.54). Additionally, only gemelli CSA was associated with BMD of the spine (p = 0.002). Gluteus maximus and piriformis showed no relationship with BMD. CSA of most hip muscles (except gluteus maximus and gemelli) were positively associated with leg strength (p = 0.02 to <0.001). Lastly, leg strength was weakly associated with BMD (p = 0.11-0.007). Hip muscle CSA, and to a lesser extent muscle strength, were positively associated with hip BMD. These data suggest that both higher muscle mass and strength may contribute to the maintenance of bone mass and prevention of disease progression in older adults.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Rheumatology and Arthritis
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Skeletal System and Disorders (incl. Arthritis)
Author:Ahedi, HK (Ms Harbeer Ahedi)
Author:Aitken, D (Dr Dawn Aitken)
Author:Blizzard, L (Associate Professor Leigh Blizzard)
Author:Jones, G (Professor Graeme Jones)
ID Code:91524
Year Published:2014
Web of Science® Times Cited:3
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-05-21
Last Modified:2016-02-01
Downloads:0

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