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Retinal detachment induces massive immediate reorganization in visual cortex

Citation

Schmid, LM and Rosa, MGP and Calford, MB, Retinal detachment induces massive immediate reorganization in visual cortex, NeuroReport, 6, (9) pp. 1349-1353. ISSN 0959-4965 (1995) [Refereed Article]

DOI: doi:10.1097/00001756-199506090-00030

Abstract

Large inactive regions of the retina of adult cats were produced by the novel method of inducing monocular retinal detachment. Within a few hours, neurones throughout the detachment projection zone in primary visual cortex (55-136 mm2), including some > 4.5 mm from its boundary, were found to have large receptive fields displaced onto intact retina. The new receptive fields of some neurones represented shifts of up to 9 mm across the retinotopic representation. For these rapid changes to occur pre-existing viable circuits must provide a cortical locus with inputs from a wide extent of the retina. Receptive fields, and the retinotopic map, for stimulation of the other eye were unchanged.

Item Details

Item Type:Refereed Article
Keywords:Cats; Reorganization; Retinal detachment; Visual cortex; animal experiment; article; cat; controlled study; electrophysiology; nerve cell plasticity; nonhuman; priority journal; receptive field; retina detachment; visual cortex; Cats
Research Division:Medical and Health Sciences
Research Group:Neurosciences
Research Field:Neurology and Neuromuscular Diseases
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Nervous System and Disorders
Author:Calford, MB (Professor Mike Calford)
ID Code:91279
Year Published:1995
Web of Science® Times Cited:38
Deposited By:Research Division
Deposited On:2014-05-13
Last Modified:2014-05-13
Downloads:0

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