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Interhemispheric transfer of plasticity in the cerebral cortex

Citation

Calford, MB and Tweedale, R, Interhemispheric transfer of plasticity in the cerebral cortex, Science, 249, (4970) pp. 805-807. ISSN 0036-8075 (1990) [Refereed Article]

DOI: doi:10.1126/science.2389146

Abstract

Each half of the body surface is represented topographically in the contralateral cerebral hemisphere. Physiological data are presented showing that homotopic regions of primary somatosensory cortex are linked such that plasticity induced in one hemisphere, in the form of receptive field expansion brought about by a small peripheral denervation, is immediately mirrored in the other hemisphere. Neurons which display the plasticity show no responsiveness to stimulation of the ipsilateral body surface. This suggests that the pathways and mechanisms mediating this transfer are specific to the role of maintaining balance, or integration, between corresponding cortical fields.

Item Details

Item Type:Refereed Article
Keywords:animal experiment; article; brain cortex; cat; hemispheric dominance; nonhuman; plasticity; priority journal; somatosensory cortex; Amputation; Anesthesia; Animal; Cerebral Cortex; Chiroptera; Denervation; Fingers; Forelimb; Human
Research Division:Medical and Health Sciences
Research Group:Neurosciences
Research Field:Neurology and Neuromuscular Diseases
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Nervous System and Disorders
Author:Calford, MB (Professor Mike Calford)
ID Code:91261
Year Published:1990
Web of Science® Times Cited:156
Deposited By:Research Division
Deposited On:2014-05-13
Last Modified:2014-05-13
Downloads:0

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