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The Unintended Implications of Blurring the Line between Research and Clinical Care in a Genomic Age


Berkman, BE and Hull, S and Eckstein, LG, The Unintended Implications of Blurring the Line between Research and Clinical Care in a Genomic Age, Personalized Medicine, 11, (3) pp. 285-295. ISSN 1741-0541 (2014) [Refereed Article]

Copyright Statement

Copyright 2014 Future Medicine Ltd

DOI: doi:10.2217/PME.14.3


While the development of next-generation sequencing technology has had a paradigmchanging impact on biomedical research, there is likely to be a gap between discovery of therapeutic benefits in research and actual adoption of the new technology into clinical practice. This gap can create pressure on the research enterprise to provide individualized care more typical of the clinic setting because it is uniquely accessible in research. This blurring of the line between research and clinical care is understandable, and perhaps even inevitable. But even if the gap is only transitory, such a blurring can have lasting implications, both by expanding obligations imposed on researchers, but also by challenging long-held ethical views. We explore this idea, focusing on how the dissolving distinction between research and clinical care has influenced the vigorous debate around how researchers should manage genetic findings (sometimes separated into primary and incidental or secondary findings) resulting from research.

Item Details

Item Type:Refereed Article
Keywords:ancillary care, incidental findings, legal liability, research ethics, secondary findings, whole-genome sequencing
Research Division:Law and Legal Studies
Research Group:Public law
Research Field:Public law not elsewhere classified
Objective Division:Culture and Society
Objective Group:Ethics
Objective Field:Technological ethics
UTAS Author:Eckstein, LG (Dr Lisa Eckstein)
ID Code:91192
Year Published:2014
Web of Science® Times Cited:20
Deposited By:Faculty of Law
Deposited On:2014-05-09
Last Modified:2015-05-01

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