Polymeric macroporous rod systemswere prepared using N-acryloyl-tris(hydroxymethyl)aminomethane (NAT) and glycidyl methacrylate (GMA) as mono-vinyl monomers and N,N-methylenebisacrylamide (BIS) or trimethylolpropane trimethacrylate (TRIM) as crosslinking agents. The reactions were performed in the presence of a ternary porogenic diluent (composed by dimethylsulfoxide, tetradecanol and poly(ethylenglycol) 6000 (PEG 6000)) and azobisisobutyronitrile (AIBN) as initiator, by freeradical crosslinking copolymerization. The effect of polymerization temperature, porogenic mixture and crosslinker was analyzed. The results showed that a lower polymerization temperature and an increase in the amount of non-solvating diluents (tetradecanol and PEG 6000) in the reaction mixture led to products with higher porosity. The prepared monolithswere promising as potential base supports for different chromatography processes, especially those synthesized with GMA, since its incorporation allows to bind different ligands in a direct coupling reaction.

Item Type:	Refereed Article
Research Division:	Chemical Sciences
Research Group:	Analytical Chemistry
Research Field:	Separation Science
Objective Division:	Expanding Knowledge
Objective Group:	Expanding Knowledge
Objective Field:	Expanding Knowledge in the Chemical Sciences
Author:	Arrua, RD (Dr Dario Arrua)
ID Code:	91075
Year Published:	2008
Web of Science® Times Cited:	7
Deposited By:	Austn Centre for Research in Separation Science
Deposited On:	2014-05-07
Last Modified:	2014-06-06
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