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Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging

Citation

Jenkins, C and Moir, S and Chan, J and Rakhit, D and Haluska, B and Marwick, TH, Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging, European Heart Journal, 30, (1) pp. 98-106. ISSN 0195-668X (2009) [Refereed Article]

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Copyright The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org.

DOI: doi:10.1093/eurheartj/ehn484

Abstract

Aims Both contrast enhanced (CE) two-dimensional echocardiography (2DE) and three-dimensional echocardiography (3DE) have been proposed as techniques to improve the accuracy of left ventricular (LV) volume measurements. We sought to examine the accuracy of non-contrast (NC) and CE-2DE and 3DE for calculation of LV volumes and ejection fraction (EF), relative to cardiac magnetic resonance imaging (MRI).
Methods and results We studied 50 patients (46 men, age 6310 year) with past myocardial infarction who underwent echocardiographic assessment of LV volume and function. All patients sequentially underwent NC-2DE followed by NC-3DE. CE-2DE and CE-3DE were acquired during contrast infusion. Resting echocardiographic image quality was evaluated on the basis of NC-2DE. The mean LV end-diastolic volume (LVEDV) of the group by MRI was 20779 mL and was underestimated by 2DE (12554 mL, P = 0.005), and less by CE-2DE (17258 mL, P = 0.02) or 3DE (17764 mL, P = 0.08), but EDV was comparable by CE-3DE (19669 mL, P = 0.16). Limits of agreement with MRI were similar for NC-3DE and CE-2DE, with the best results for CE-3D. Results were similar for calculation of LVESV. Patients were categorized into groups of EF (≤35, 3550, .50%) by MRI. NC-2DE demonstrated a 68% agreement (kappa 0.45, P = 0.001), CE-2DE a 62% agreement (kappa 0.20, P = 136), NC-3DE a 74% agreement (kappa 0.39, P = 0.005) and CE-3DE an 80% agreement (kappa 0.56, P < 0.001).
Conclusion CE-2DE is analogous to NC-3DE in accurate categorization of LV function. However, CE-3DE is feasible and superior to other NC- and CE-techniques in patients with previous infarction.

Item Details

Item Type:Refereed Article
Keywords:contrast-enhancement, left ventricular volumes, two-dimensional echocardiography, three-dimensional echocardiography
Research Division:Medical and Health Sciences
Research Group:Cardiorespiratory Medicine and Haematology
Research Field:Cardiology (incl. Cardiovascular Diseases)
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Marwick, TH (Professor Tom Marwick)
ID Code:90801
Year Published:2009
Web of Science® Times Cited:103
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-04-24
Last Modified:2014-05-13
Downloads:0

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