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Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging

Citation

Jenkins, C and Moir, S and Chan, J and Rakhit, D and Haluska, B and Marwick, TH, Left ventricular volume measurement with echocardiography: a comparison of left ventricular opacification, three-dimensional echocardiography, or both with magnetic resonance imaging, European Heart Journal, 30, (1) pp. 98-106. ISSN 0195-668X (2009) [Refereed Article]

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Copyright The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org.

DOI: doi:10.1093/eurheartj/ehn484

Abstract

Aims Both contrast enhanced (CE) two-dimensional echocardiography (2DE) and three-dimensional echocardiography (3DE) have been proposed as techniques to improve the accuracy of left ventricular (LV) volume measurements. We sought to examine the accuracy of non-contrast (NC) and CE-2DE and 3DE for calculation of LV volumes and ejection fraction (EF), relative to cardiac magnetic resonance imaging (MRI).
Methods and results We studied 50 patients (46 men, age 63+-10 year) with past myocardial infarction who underwent echocardiographic assessment of LV volume and function. All patients sequentially underwent NC-2DE followed by NC-3DE. CE-2DE and CE-3DE were acquired during contrast infusion. Resting echocardiographic image quality was evaluated on the basis of NC-2DE. The mean LV end-diastolic volume (LVEDV) of the group by MRI was 207+-79 mL and was underestimated by 2DE (125+-54 mL, P = 0.005), and less by CE-2DE (172+-58 mL, P = 0.02) or 3DE (177+-64 mL, P = 0.08), but EDV was comparable by CE-3DE (196+-69 mL, P = 0.16). Limits of agreement with MRI were similar for NC-3DE and CE-2DE, with the best results for CE-3D. Results were similar for calculation of LVESV. Patients were categorized into groups of EF (<=35, 35-50, .50%) by MRI. NC-2DE demonstrated a 68% agreement (kappa 0.45, P = 0.001), CE-2DE a 62% agreement (kappa 0.20, P = 136), NC-3DE a 74% agreement (kappa 0.39, P = 0.005) and CE-3DE an 80% agreement (kappa 0.56, P < 0.001).
Conclusion CE-2DE is analogous to NC-3DE in accurate categorization of LV function. However, CE-3DE is feasible and superior to other NC- and CE-techniques in patients with previous infarction.

Item Details

Item Type:Refereed Article
Keywords:contrast-enhancement; left ventricular volumes; two-dimensional echocardiography; three-dimensional echocardiography
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Marwick, TH (Professor Tom Marwick)
ID Code:90801
Year Published:2009
Web of Science® Times Cited:170
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-04-24
Last Modified:2022-09-01
Downloads:0

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