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Strain rate evaluation of phasic atrial function in hypertension

journal contribution
posted on 2023-05-17, 23:56 authored by Eshoo, S, Boyd, AC, Ross, DL, Thomas MarwickThomas Marwick, Thomas, L
Background: Strain (SI) and strain rate (SR) measure regional myocardial deformation and may be a new technique to assess phasic atrial function.
Objective: To examine the feasibility of using SI and SR to evaluate phasic atrial function in patients with mild hypertension (HT).
Patients and methods: The study group comprised 54 patients with mild essential HT (29 women) and 80 age-matched normal controls (47 women). Standard two-dimensional and Doppler echocardiography was performed as well as Doppler tissue imaging. The following left atrial (LA) volumes were measured: (a) maximal LA volume or Volmax; (b) minimal LA volume or Volmin; (c) just before the ‘‘p’’ wave on ECG (Volp). Phasic LA volumes were also calculated. Systolic (S-Sr), early diastolic (E-Sr), late diastolic (A-Sr) strain rate and SI were measured.
Results: Despite no differences in indexed maximal LA volume with only mild increases in left ventricular mass in the HT cohort compared with normal subjects (mean (SD) 86 (18) g/m2 vs 67 (14) g/m2; p=0.001), E-Sr was significantly lower in the HT cohort. There was a corresponding reduction in indexed conduit volume in the HT cohort compared with normal subjects (10.5 (7.5) ml/m2 vs 13.8 (6.1) ml/m2; p=0.006). Global E-Sr showed modest negative correlations with LA Volmax and LA ejection fraction. No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts.
Conclusion: Mild HT results in a reduction in LA conduit volume, although maximal LA volume is unchanged. This is reflected by a reduction in E-Sr with preserved S-Sr andA-Sr.

History

Publication title

Heart

Volume

95

Issue

14

Pagination

1184-1191

ISSN

1355-6037

Department/School

Menzies Institute for Medical Research

Publisher

B M J Publishing Group

Place of publication

British Med Assoc House, Tavistock Square, London, England, Wc1H 9Jr

Rights statement

Copyright 2009 BMJ

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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