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Baseline and follow-up assessment of regional left ventricular volume using 3-dimensional echocardiography: comparison with cardiac magnetic resonance

Citation

Jenkins, C and Marwick, TH, Baseline and follow-up assessment of regional left ventricular volume using 3-dimensional echocardiography: comparison with cardiac magnetic resonance, Cardiovascular Ultrasound, 7, (1) Article 55. ISSN 1476-7120 (2009) [Refereed Article]


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Copyright Statement

Copyright 2009 Jenkins and Marwick; licensee BioMed Central Ltd

DOI: doi:10.1186/1476-7120-7-55

Abstract

The assessment of regional volumes is an option for analysis of the response of LV segments to interventions such as revascularization or cell therapy. We sought to compare regional volumes from 3D-echocardiography (3DE) with cardiac magnetic resonance (CMR) over follow-up.

CMR regional volumes were assessed at baseline and after one year follow-up in 30 unselected patients (28 men, 65 11 years) presenting for evaluation of cardiac function with previous infarction. 3DE images were also gathered over 4 cardiac cycles and measurements were performed off-line. CMR images were obtained using a 1.5 Tesla scanner and measured offline by method of landmarks and by centre of mass. Regional volumes were measured at end-diastole (rEDV) and end-systole (rESV) and the change in volume was compared for each over follow-up.

There was good correlation between 3DE and both CMR methods at baseline and follow-up. Changes in rEDV with 3DE vs CMRL were comparable (0.11 3 ml vs 0.12 3 ml, p = 0.94), as was change in CMRM (0.26 2 ml, p = 0.69). However the change in regional volume by 3DE and CMRL correlated poorly (r = 0.03, p = 0.68), as did change in 3DE vs CMRM (r = 0.04, p = 0.65). Similarly, changes in rESV with 3DE and CMRL were similar (0.27 2 ml vs 0.36 2 ml, p = 0.70), as was change in CMRM (0.05 1 ml, p = 0.31). Again, correlations between rESV by 3DE vs CMRL were poor (r = 0.03, p = 0.72), as well as 3DE vs CMRM (r = 0.07, p = 0.40).

Although global 3DE volumes compare well with CMR volumes, new developments in image quality and automated software will be needed before changes in regional volumes can be reliably followed with 3DE.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Cardiorespiratory Medicine and Haematology
Research Field:Cardiology (incl. Cardiovascular Diseases)
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Marwick, TH (Professor Tom Marwick)
ID Code:90745
Year Published:2009
Web of Science® Times Cited:7
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-04-23
Last Modified:2014-05-16
Downloads:199 View Download Statistics

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