eCite Digital Repository

Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study


Fukuda, S and Watanabe, H and Daimon, M and Abe, Y and Hirashiki, A and Hirata, K and Ito, H and Iwai-Takano, M and Iwakura, K and Izumi, C and Hidaka, T and Yuasa, T and Murata, K and Nakatani, S and Negishi, K and Nishigami, K and Nishikage, T and Ota, T and Hayashida, A and Sakata, K and Tanaka, N and Yamada, S and Yamamoto, K and Yoshikawa, J, Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study, Circulation Journal, 76, (5) pp. 1177-1181. ISSN 1346-9843 (2012) [Refereed Article]

Restricted - Request a copy

Copyright Statement

Copyright 2012 The Japanese Circulation Society

DOI: doi:10.1253/circj.CJ-11-1256


Background: The recently developed real-time 3-dimensional echocardiography (RT3DE) is a promising imaging method to quantify cardiac chamber volumes and their functions in clinical practice. However, normal reference values of RT3DE parameters have not been fully investigated in a large, healthy Japanese population.

Methods and Results: This study consisted of 410 healthy subjects aged from 20 to 69 years who had a RT3DE at one of the 23 collaborating institutions. All subjects had no history of cardiac disease and no risk factors. The mean values in men and women were as follows: 5012ml/m2 and 469ml/m2 for left ventricular (LV) end-diastolic volume index, 195ml/m2 and 174ml/m2 for end-systolic volume index, 614% and 634% for ejection fraction, 6412g/m2 and 5611g/m2 for mass index, 236ml/m2 and 246ml/m2 for left atrial (LA) maximum volume index, 103ml/m2 and 103ml/m2 for minimum volume index, and 586% and 586% for percent volume change. LV sizes decreased with age, whereas LV mass index did not change. LA sizes slightly increased with age.

Conclusions: This multicenter investigation determined normal reference values for LV and LA sizes, and their functional parameters on RT3DE in a large, healthy Japanese population. The results of the present study support the use of RT3DE for the diagnosis and management of cardiovascular disease.

Item Details

Item Type:Refereed Article
Keywords:echocardiography, Japanese, population
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Negishi, K (Dr Kazuaki Negishi)
ID Code:90050
Year Published:2012
Web of Science® Times Cited:64
Deposited By:Menzies Institute for Medical Research
Deposited On:2014-03-25
Last Modified:2017-11-03

Repository Staff Only: item control page