Daimon, M and Watanabe, H and Abe, Y and Hirata, K and Hozumi, T and Ishii, K and Ito, H and Iwakura, K and Izumi, C and Matsuzaki, M and Minagoe, S and Abe, H and Murata, K and Nakatani, S and Negishi, K and Yoshida, K and Tanabe, K and Tanaka, N and Tokai, K and Yoshikawa, J, Normal values of echocardiographic parameters in relation to age in a healthy Japanese population - The JAMP study, Circulation Journal, 72, (11) pp. 1859-1866. ISSN 1346-9843 (2008) [Refereed Article]
Copyright 2008 The Japanese Circulation Society
Background: Normal values for echocardiographic measurements and the relationship between these parameters and age in a large Japanese population are still unknown.
Methods and Results: A total of 700 healthy Japanese aged 20-79 years underwent 2-dimensional and Doppler echocardiography at collaborating institutions. The respective mean values obtained in men and women were as follows: septal wall thickness, 0.9 ± 0.1 and 0.8 ± 0.1 cm; posterior wall thickness, 0.9 ± 0.1 and 0.8 ± 0.1cm; left ventricular (LV) diastolic diameter, 4.8 ± 0.4 and 4.4 ± 0.3 cm; LV systolic diameter, 3.0 ± 0.4 and 2.8 ± 0.3cm; LV diastolic volume, 93 ± 20 and 74 ± 17 ml; LV systolic volume, 33 ± 20 and 25 ± 7 ml; LV ejection fraction, 64 ± 5 and 66 ± 5%; maximum left atrial (LA) volume, 42 ± 14 and 38 ± 12 ml. Aortic root diameter, LV wall thickness, and LV mass slightly increased with age, whereas indexed LA volume did not vary with age. Diastolic parameters assessed by mitral inflow and mitral annular velocities declined with age, as previously reported.
Conclusions: Normal values of echocardiographic measurements in a large Japanese population are reported for the first time; several systolic and diastolic parameters varied with age. These results provide important reference values that should be useful in routine clinical practice as well as in clinical trials.
|Item Type:||Refereed Article|
|Keywords:||cardiac volume, echocardiography, ventricular function|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Cardiovascular medicine and haematology|
|Research Field:||Cardiology (incl. cardiovascular diseases)|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Negishi, K (Dr Kazuaki Negishi)|
|Web of Science® Times Cited:||145|
|Deposited By:||Menzies Institute for Medical Research|
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